Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Rabbit Polyclonal (IgG) to Human PDGFRA / PDGFR Alpha
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Hamster, Horse, Pig, Rabbit, Chicken, Xenopus
IHC, IHC - Paraffin, Western blot, Immunoprecipitation
Rabbit Monoclonal (IgG) to Human PDGFRA / PDGFR Alpha
IHC, IHC - Paraffin, Immunofluorescence, Western blot, Immunoprecipitation, Flow Cytometry
Human PDGFRA / PDGFR Alpha
Human, Mouse (tested or 100% immunogen sequence identity)
IHC - Paraffin
Western blot (1:1000)
Flow Cytometry (1:1000)
Specificity and Use
Synthetic peptide (KLH-coupled) corresponding to residues near the carboxy-terminal sequence of human PDGFR.
Detects endogenous levels of PDGFRA. This anti-body may cross-react with PDGFRB at overexpressed levels.
Suitable for use in Western Blot, Immunoprecipitation and Immunohistochemistry, Immunofluorescence and Flow Cytometry. Western Blot: 1:1000. Immunohistochemistry (Paraffin): 1:500. Antigen retrieval: heat in citrate buffer, pH 6.0. Immunoprecipitation: 1:50. Immunofluorescence (IF-IC): 1:1000. Flow Cytometry: 1:1000.
10 mM sodium HEPES, pH 7.5, 150 mM sodium chloride, 100 ug/ml BSA, 50% glycerol, 0.02% sodium azide.
Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development and cephalic closure during embryonic development.