PDGF-BB

platelet-derived growth factor beta polypeptide

PDGF-BB is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 17, at sites where this gene and that for collagen type 1, alpha 1 are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans resulting from unregulated expression of growth factor. Two alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

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Products

Antibodies (92)

ELISA Kits (61)

Proteins (34)

Type

Cell-Based (1)

Competitive EIA (2)

Custom (1)

Development Kit (2)

Over-Expression Cell Culture Supernatant (1)

Over-Expression Lysate (6)

Primary (92)

Recombinant (27)

Sandwich (47)

Sandwich CLIA (8)

Target

PDGF-BB (187)

Reactivity

Human (84)

Mouse (55)

Rat (39)

Bat (3)

Bovine (5)

Canine (1)

Chicken (1)

Chimpanzee (3)

Cow (1)

Dog (4)

Equine (1)

Guinea pig (4)

Monkey (3)

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IHC (20)

IHC-P (8)

WB (89)

ELISA (15)

ICC (1)

IF (4)

Peptide-ELISA (3)

Host

rabbit (82)

mouse (9)

goat (1)

Product Group

DevKit Core (2)

IHCPlus (4)

Isotype

IgG (27)

IgG1 (1)

Clonality

monoclonal mc (9)

polyclonal pc (83)

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1000 Wells (1)

12 x 8-Well Microstrips (6)

200 Wells (1)

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Atto 390 Conjugated (2)

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Atto 594 Conjugated (1)

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Cy7 Conjugated (5)

FITC Conjugated (9)

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PerCP Conjugated (2)

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Epitope

aa82-190 (25)

aa21-241 (8)

aa5-225 (8)

aa212-241 (7)

N-Terminus (4)

30-110 aa, Internal (1)

Internal (1)

aa16-65 (1)

aa21-70 (1)

aa222-233 (1)

Publications

No (185)

Yes (2)

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Adherent Cell Cultures (1)

Cell Culture Supernatants (13)

Cell Lysates (5)

EDTA Plasma (3)

Heparin Plasma (3)

Plasma (49)

Platelet-Poor Plasma (1)

Serum (50)

Tissue Homogenates (18)

Tag

6His, C-terminus (2)

6His, N-terminus (4)

GST, N-terminus (1)

His (1)

His, N-Terminal (2)

His, N-terminus (1)

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Human (19)

Mouse (10)

Rat (3)

Source

293T Cells (2)

E. coli (24)

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Wheat Germ Extract (1)

Yeast (2)

Purification

Purified (7)

Low Endotoxin Level

Low endotoxin level (16)

Biologically Active

Biologically active (12)

Animal-free

Animal-free (1)

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IHC-plus™ PDGF-BB Antibody (aa222-233) LS-B4182

(5.0) Rating

(2) Publication(s)

Antibody:

PDGF-BB Goat anti-Human Polyclonal (aa222-233) Antibody

Reactivity:

Sheep, Bovine, Human

Applications:

IF, IHC, IHC-P, Peptide-ELISA

Format:

Unconjugated

Price:

50 µg/$485

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PDGF-BB Antibody LS-C201038

(4.0) Rating

(1) Publication(s)

Antibody:

PDGF-BB Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

0.1 mg/$460

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PDGF-BB Antibody (N-Terminus) LS-B6945

Antibody:

PDGF-BB Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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PDGF-BB Antibody (N-Terminus, HRP) LS-C465127

Antibody:

PDGF-BB Rabbit anti-Human Polyclonal (N-Terminus) (HRP) Antibody

Reactivity:

Xenopus, Bat, Rat, Rabbit, Mouse, Dog, Guinea pig, Sheep, Bovine, Human, Chimpanzee

Applications:

IHC, IHC-P, WB

Format:

HRP Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP

• Unconjugated
• HRP

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PDGF-BB Antibody LS-C104675

Antibody:

PDGF-BB Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$356; 100 µg/$396

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PDGF-BB Antibody (Biotin) LS-C104638

Antibody:

PDGF-BB Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

25 µg/$356; 50 µg/$396

• Unconjugated
• Biotin

• Unconjugated
• Biotin

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PDGF-BB Antibody LS-C331340

Antibody:

PDGF-BB Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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Monkey PDGF-BB (Sandwich ELISA) ELISA Kit - LS-F46948

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Monkey

Range:

31.25 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$863

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PDGF-BB Antibody LS-C38273

Antibody:

PDGF-BB Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$842

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PDGF-BB Antibody (aa82-190) LS-C314198

Antibody:

PDGF-BB Mouse anti-Human Monoclonal (aa82-190) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$305; 200 µl/$345; 500 µl/$479; 1 ml/$547; 2 ml/$725; 5 ml/$1,192

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PDGF-BB Antibody (aa82-190, FITC) LS-C417894

Antibody:

PDGF-BB Mouse anti-Human Monoclonal (aa82-190) (FITC) Antibody

Reactivity:

Human

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$342; 200 µl/$399; 500 µl/$587; 1 ml/$725; 2 ml/$962; 5 ml/$1,647

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PDGF-BB Antibody (aa82-190, Cy3) LS-C698877

Antibody:

PDGF-BB Mouse anti-Human Monoclonal (aa82-190) (Cy3) Antibody

Reactivity:

Human

Applications:

WB

Format:

Cy3 Conjugated

Price:

100 µl/$399; 200 µl/$479; 500 µl/$822; 1 ml/$978; 2 ml/$1,255; 5 ml/$2,353

• Unconjugated
• FITC
• Cy3

• Unconjugated
• FITC
• Cy3

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IHC-plus™ PDGF-BB Antibody (aa21-70) LS-B10929

(4.0) Rating

Antibody:

PDGF-BB Rabbit anti-Human Polyclonal (aa21-70) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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IHC-plus™ PDGF-BB Antibody LS-B14260

(4.0) Rating

Antibody:

PDGF-BB Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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Cow PDGF-BB (Sandwich ELISA) ELISA Kit - LS-F54885

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Cow

Range:

15.6 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$968

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Human PDGF-BB (Sandwich ELISA) ELISA Kit - LS-F12289

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

31.2 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$685

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Mouse PDGF-BB Protein (Over-Expression Lysate 6His, N-terminus) (Ser82-Thr190) - LS-G26804

Source:

HEK 293 Cells

Tag:

6His, N-terminus

Molecular Weight:

15 kDa

Price:

100 µg/$298

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PDGF-BB Antibody (aa21-241, Biotin) LS-C300513

Antibody:

PDGF-BB Rabbit anti-Mouse Polyclonal (aa21-241) (Biotin) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$311; 200 µl/$353; 500 µl/$496; 1 ml/$567; 2 ml/$769; 5 ml/$1,248

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PDGF-BB Antibody (aa5-225) LS-C295957

Antibody:

PDGF-BB Rabbit anti-Rat Polyclonal (aa5-225) Antibody

Reactivity:

Rat

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$306; 200 µl/$347; 500 µl/$484; 1 ml/$553; 2 ml/$737; 5 ml/$1,206

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Rat PDGF-BB (Sandwich ELISA) ELISA Kit - LS-F13378

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

31.2 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$685

Select

Human PDGF-BB Protein (Recombinant 6His, N-terminus) - LS-G26392

Source:

E. coli

Tag:

6His, N-terminus

Molecular Weight:

12 kDa

Price:

10 µg/$265; 50 µg/$315; 100 µg/$365

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PDGF-BB Antibody LS-C800359

Antibody:

PDGF-BB Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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PDGF-BB Antibody LS-C827148

Antibody:

PDGF-BB Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

Select

PDGF-BB Antibody (aa16-65) LS-C118554

Antibody:

PDGF-BB Rabbit anti-Human Polyclonal (aa16-65) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

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PDGF-BB Antibody (aa212-241, Azide-free, HRP) LS-C281037

Antibody:

PDGF-BB Rabbit anti-Human Polyclonal (aa212-241) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

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