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Anti-PDE7A Antibody (N-Terminus) IHC-plus™ LS-A703

Note: This antibody replaces LS-C90186, LS-C42452

Ordering

Wt. Vol. Conc. Price
50 µg - 0.4 mg/ml $395
Inquire for larger quantities
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LSBio (Direct) LSBio (Direct)
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Rabbit Polyclonal to Human PDE7A
Human, Monkey, Bat, Bovine, Dog, Rabbit, Xenopus
IHC - Paraffin
Unconjugated

Details

Human PDE7A
Rabbit
Human, Monkey, Bat, Bovine, Dog, Rabbit, Xenopus (tested or 100% immunogen sequence identity)
Mouse, Rat, Hamster (at least 90% immunogen sequence identity)
Polyclonal
Immunoaffinity purified

Applications

IHC - Paraffin (20 µg/ml)

Specificity and Use

PDE7A antibody was raised against synthetic 17 amino acid peptide from N-terminus of human PDE7A. Percent identity with other species by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Bovine, Dog, Bat, Elephant, Panda, Rabbit, Opossum, Xenopus (100%); Mouse, Rat, Hamster, Turkey, Lizard (94%); Zebrafish (82%).
LS-E29215 - Liquid - 50 µg - $145.00
N-Terminus
Human PDE7A. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Immunohistochemistry: LS-A703 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-A703 was determined to be 20 ug/ml.

Packaging

PBS, less than 0.1% sodium azide.
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze thaw cycles.
For research use only.

About PDE7A

Q13946 L12052 AAA35644.2

PDE7A Antibody, PDE7A1 Antibody, PDE7A2 Antibody, Phosphodiesterase 7A Antibody, Phosphodiesterase isozyme 7 Antibody, PDE7 Antibody, HCP1 Antibody, TM22 Antibody

PDE7A belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE7 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Immunohistochemistry

Immunohistochemistry
Anti-PDE7A antibody LS-A703 IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
 

Requested From: United States
Date Requested: 9/29/2016

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