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Anti-PDE11A Antibody (Internal) IHC-plus™ LS-A746

Note: This antibody replaces LS-C42465


Wt. Vol. Conc. Price
50 µg 218 µl 0.23 mg/ml $395
Inquire for larger quantities
Same day shipping In Stock - Same day shipping

LSBio (Direct) LSBio (Direct)

Most Popular PDE11A Antibodies

Anti-PDE11A Antibody (Internal) IHC-plus™ LS-A746
Rabbit Polyclonal to Human PDE11A
Human, Monkey, Mouse, Rat, Bat, Bovine, Hamster, Horse, Pig, Rabbit, Chicken, Zebrafish
IHC - Paraffin
Immunohistochemistry Image
Anti-PDE11A Antibody (aa455-468) IHC-plus™ LS-B2676
Goat Polyclonal to Human PDE11A
Human, Monkey, Bat, Bovine, Dog, Pig
IHC - Paraffin, Western blot, ELISA
Immunohistochemistry Image
Anti-PDE11A Antibody (aa33-63, AP) LS-C216659
Rabbit Polyclonal (IgG) to Human PDE11A
Human, Mouse
IHC, Western blot, ELISA
AP Conjugated

100% Guaranteed 100% Guaranteed In Stock In Stock
Rabbit Polyclonal to Human PDE11A
Human, Monkey, Mouse, Rat, Bat, Bovine, Hamster, Horse, Pig, Rabbit, Chicken, Zebrafish
IHC - Paraffin


Human PDE11A
Human, Monkey, Mouse, Rat, Bat, Bovine, Hamster, Horse, Pig, Rabbit, Chicken, Zebrafish (tested or 100% immunogen sequence identity)
Xenopus (at least 90% immunogen sequence identity)
Immunoaffinity purified


IHC - Paraffin (5 µg/ml)

Specificity and Use

PDE11A antibody was raised against synthetic 17 amino acid peptide from internal region of human PDE11A. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Bovine, Bat, Hamster, Elephant, Horse, Rabbit, Pig, Opossum, Turkey, Chicken, Pufferfish, Zebrafish (100%); Platypus, Xenopus, Stickleback (94%); Dog (88%).
Human PDE11A. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except PDE6B (53%).
Immunohistochemistry: LS-A746 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-A746 was determined to be 5 ug/ml.


PBS, less than 0.1% sodium azide.
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze thaw cycles.
For research use only.

About PDE11A

Q9HCR9 NM_016953 AAI12394.1

PDE11A Antibody, Pde11 Antibody, PDE11A4 Antibody, PDE11A1 Antibody, PPNAD2 Antibody, PDE11A2 Antibody, PDE11A3 Antibody, Phosphodiesterase 11A Antibody

The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a member of the PDE protein superfamily. Mutations in this gene are a cause of Cushing disease and adrenocortical hyperplasia.


Anti-PDE11A antibody LS-A746 IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Requested From: United States
Date Requested: 10/27/2016

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