PDCD6IP / ALIX

programmed cell death 6 interacting protein

Class E VPS protein involved in concentration and sorting of cargo proteins of the multivesicular body (MVB) for incorporation into intralumenal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome. Binds to the phospholipid lysobisphosphatidic acid (LBPA) which is abundant in MVBs internal membranes. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and enveloped virus budding (HIV-1 and other lentiviruses). Appears to be an adapter for a subset of ESCRT-III proteins, such as CHMP4, to function at distinct membranes. Required for completion of cytokinesis. Involved in HIV-1 virus budding. Can replace TSG101 it its role of supporting HIV-1 release; this function implies the interaction with CHMP4B. May play a role in the regulation of both apoptosis and cell proliferation.

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Products

Antibodies (45)

Proteins (8)

ELISA Kits (2)

Type

Over-Expression Lysate (2)

Primary (45)

Recombinant (6)

Sandwich (2)

Target

PDCD6IP / ALIX (55)

Reactivity

Human (38)

Mouse (22)

Rat (12)

Frog (1)

Xenopus (6)

Application

IHC (13)

IHC-P (5)

WB (45)

ELISA (15)

IF (8)

IP (9)

Peptide-ELISA (1)

Host

rabbit (33)

mouse (12)

Product Group

IHCPlus (1)

Isotype

IgG (12)

IgG1 (7)

IgG1,k (3)

IgG2a (2)

Clonality

monoclonal mc (12)

polyclonal pc (33)

Clone

3A9 (2)

8E8 (2)

G1/G1-4 (1)

OTI1A4 (2)

Format

96-Well Strip Plate (2)

APC (2)

APC Conjugated (3)

Azide-free (1)

Biotin Conjugated (4)

Carrier-free (1)

Cy3 Conjugated (2)

Cy7 Conjugated (2)

FITC Conjugated (4)

HRP Conjugated (4)

PE Conjugated (4)

Unconjugated (22)

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Epitope

aa1-239 (8)

aa174-383 (8)

aa541-570 (7)

aa2-330 (1)

aa818-868 (1)

Publications

No (54)

Yes (1)

Sample Type

Cell Lysates (2)

Plasma (1)

Serum (1)

Tissue Homogenates (2)

Tag

GST (1)

GST, N-terminus (1)

His (1)

His-GST-S (1)

His-T7 (1)

Myc-DDK (Flag) (3)

Species

Human (6)

Mouse (1)

Source

293T Cells (1)

E. coli (3)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (1)

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PDCD6IP / ALIX Antibody (clone 3A9) LS-C41064

(4.0) Rating

(1) Publication(s)

Antibody:

PDCD6IP / ALIX Mouse anti-Human Monoclonal (3A9) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

25 µg/$283; 100 µg/$357

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PDCD6IP / ALIX Antibody LS-C490441

Antibody:

PDCD6IP / ALIX Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$575

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Human PDCD6IP / ALIX (Sandwich ELISA) ELISA Kit - LS-F52391

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

47 - 3000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$958

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Human PDCD6IP / ALIX (Sandwich ELISA) ELISA Kit - LS-F7886

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$798

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Human PDCD6IP / ALIX Protein (Recombinant GST) (Full Length) - LS-G31900

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

121.11 kDa

Price:

10 µg/$479; 25 µg/$670

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IHC-plus™ PDCD6IP / ALIX Antibody (aa818-868) LS-B12349

(4.0) Rating

Antibody:

PDCD6IP / ALIX Rabbit anti-Human Polyclonal (aa818-868) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, IP, WB

Format:

Unconjugated

Price:

100 µl/$485

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PDCD6IP / ALIX Antibody (clone 8E8) LS-C153291

Antibody:

PDCD6IP / ALIX Mouse anti-Human Monoclonal (8E8) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$440; 100 µg/$468

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PDCD6IP / ALIX Antibody LS-C331993

Antibody:

PDCD6IP / ALIX Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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PDCD6IP / ALIX Antibody LS-C121356

Antibody:

PDCD6IP / ALIX Mouse Monoclonal Antibody

Reactivity:

Xenopus, Rat, Mouse, Human

Applications:

ELISA, IF, IHC, IHC-P, IP, WB

Format:

Unconjugated

Price:

100 µg/$611

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PDCD6IP / ALIX Antibody (HRP) LS-C543419

Antibody:

PDCD6IP / ALIX Mouse anti-Human Monoclonal (HRP) Antibody

Reactivity:

Xenopus, Rat, Mouse, Human

Applications:

ELISA, IF, IHC, IP, WB

Format:

HRP Conjugated

Price:

100 µl/$848

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PDCD6IP / ALIX Antibody (Biotin) LS-C523292

Antibody:

PDCD6IP / ALIX Mouse anti-Human Monoclonal (Biotin) Antibody

Reactivity:

Xenopus, Rat, Mouse, Human

Applications:

ELISA, IF, IHC, IP, WB

Format:

Biotin Conjugated

Price:

100 µl/$848

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PDCD6IP / ALIX Antibody (FITC) LS-C533333

Antibody:

PDCD6IP / ALIX Mouse anti-Human Monoclonal (FITC) Antibody

Reactivity:

Xenopus, Rat, Mouse, Human

Applications:

ELISA, IF, IHC, IP, WB

Format:

FITC Conjugated

Price:

100 µl/$848

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PDCD6IP / ALIX Antibody (PE) LS-C651531

Antibody:

PDCD6IP / ALIX Mouse anti-Human Monoclonal (PE) Antibody

Reactivity:

Xenopus, Rat, Mouse, Human

Applications:

ELISA, IF, IHC, IP, WB

Format:

PE Conjugated

Price:

100 µl/$848

• Unconjugated
• HRP
• Biotin
• FITC
• PE

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • PE

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PDCD6IP / ALIX Antibody (clone OTI1A4) LS-C338469

Antibody:

PDCD6IP / ALIX Mouse anti-Human Monoclonal (OTI1A4) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$434

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PDCD6IP / ALIX Antibody (clone OTI1A4, Carrier-free) LS-C788555

Antibody:

PDCD6IP / ALIX Mouse anti-Human Monoclonal (Carrier-free) (OTI1A4) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

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PDCD6IP / ALIX Antibody LS-C667540

Antibody:

PDCD6IP / ALIX Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IP, WB

Format:

Unconjugated

Price:

100 µg/$331

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PDCD6IP / ALIX Antibody (clone 3A9) LS-C44918

Antibody:

PDCD6IP / ALIX Mouse Monoclonal (3A9) Antibody

Reactivity:

Xenopus, Rat, Mouse, Human

Applications:

ELISA, IF, IHC-P, IP, WB

Format:

Unconjugated

Price:

0.1 mg/$395

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Mouse PDCD6IP / ALIX Protein (Recombinant His-T7) (aa1-239) - LS-G13544

Source:

E. coli

Tag:

His-T7

Molecular Weight:

30.3 kDa

Price:

10 µg/$276; 50 µg/$412; 100 µg/$657; 200 µg/$822; 1 mg/$1,905; 500 µg/$1,455; 5 mg/$2,871; 2 mg/$2,090

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PDCD6IP / ALIX Antibody (clone G1/G1-4) LS-C189649

Antibody:

PDCD6IP / ALIX Mouse anti-Human Monoclonal (G1/G1-4) Antibody

Reactivity:

Frog, Mouse, Human

Applications:

IF, IP, WB

Format:

Unconjugated

Price:

25 µg/$473; 100 µg/$657

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PDCD6IP / ALIX Antibody (clone 8E8) LS-C759949

Antibody:

PDCD6IP / ALIX Mouse anti-Human Monoclonal (8E8) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

100 µg/$575

Select

PDCD6IP / ALIX Antibody (aa2-330) LS-C407982

Antibody:

PDCD6IP / ALIX Rabbit anti-Human Polyclonal (aa2-330) Antibody

Reactivity:

Mouse, Human

Applications:

IHC-P, WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

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PDCD6IP / ALIX Antibody LS-C768922

Antibody:

PDCD6IP / ALIX Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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PDCD6IP / ALIX Antibody (aa541-570) LS-C323879

Antibody:

PDCD6IP / ALIX Rabbit anti-Human Polyclonal (aa541-570) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

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PDCD6IP / ALIX Antibody (aa541-570, Biotin) LS-C238884

Antibody:

PDCD6IP / ALIX Rabbit anti-Human Polyclonal (aa541-570) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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PDCD6IP / ALIX Antibody (aa541-570, PE) LS-C238888

Antibody:

PDCD6IP / ALIX Rabbit anti-Human Polyclonal (aa541-570) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• PE

• Unconjugated
• Biotin
• PE

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