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PDCD6 / ALG-2

programmed cell death 6

Calcium-binding protein required for T-cell receptor-, Fas-, and glucocorticoid-induced cell death. May mediate Ca2+-regulated signals along the death pathway (By similarity). Calcium-dependent adapter necessary for the association between PDCD6IP and TSG101. Interaction with DAPK1 can accelerate apoptotic cell death by increasing caspase-3 activity. May inhibit KDR/VEGFR2-dependent angiogenesis; the function involves inhibition of VEGF-induced phosphoprylation of the Akt signaling pathway. Seems to play a role in the regulation of the distribution and function of MCOLN1 in the endosomal pathway. Isoform 2 has a lower Ca2+ affinity than isoform 1. Isoform 1 and, to a lesser extend, isoform 2, can stabilize SHISA5.

Gene Name: programmed cell death 6
Synonyms: PDCD6, PEF1B, Programmed cell death 6, ALG-2
Target Sequences: NM_013232 NP_037364.1 O75340

☰ Filters
Antibodies (27)
Proteins (8)
ELISA Kits (1)
Over-Expression Lysate (2)
Primary (27)
Recombinant (6)
Sandwich (1)
PDCD6 / ALG-2 (36)
Human (27)
Mouse (6)
Rat (3)
IHC (8)
IHC-P (2)
WB (27)
ELISA (13)
ICC (2)
IF (3)
IP (2)
Peptide-ELISA (1)
rabbit (27)
Product Group
IHCPlus (1)
IgG (16)
polyclonal pc (27)
96-Well Strip Plate (1)
APC (1)
APC Conjugated (2)
Azide-free (1)
Biotin Conjugated (3)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (2)
Unconjugated (12)
aa32-191 (8)
aa19-47 (7)
aa103-137 (1)
No (36)
Tissue Homogenates (1)
GST (2)
GST, N-terminus (1)
His (1)
His-S (1)
Myc-DDK (Flag) (3)
Human (7)
293T Cells (1)
E. coli (3)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (1)
PDCD6 / ALG-2 Antibody - Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE), at a dilution of 1:100.
Select
PDCD6 / ALG-2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, WB
Unconjugated
50 µl/$460
PDCD6 / ALG-2 Antibody - Immunohistochemical analysis of ALG-2 staining in rat kidney formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Select
PDCD6 / ALG-2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
50 µl/$286; 100 µl/$321; 200 µl/$386
Select
PDCD6 / ALG-2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
60 µl/$343; 120 µl/$427; 200 µl/$559
PDCD6 / ALG-2 Antibody - IHC image of PDCD6 Antibody diluted at 1:200 and staining in paraffin-embedded human liver cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
Select
PDCD6 / ALG-2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µg/$294; 100 µg/$360
Select
PDCD6 / ALG-2 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated
50 µg/$294; 100 µg/$360
Select
PDCD6 / ALG-2 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
50 µg/$294; 100 µg/$360
Select
PDCD6 / ALG-2 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
50 µg/$294; 100 µg/$360
PDCD6 / ALG-2 Antibody - Western blot of PDCD6 / ALG-2 antibody.
Select
PDCD6 / ALG-2 Rabbit anti-Human Polyclonal (aa32-191) Antibody
Human
ICC, IP, WB
Unconjugated
100 µl/$319; 200 µl/$365; 500 µl/$519; 1 ml/$597; 2 ml/$826; 5 ml/$1,352
PDCD6 / ALG-2 Antibody - Western blot of PDCD6 / ALG-2 antibody.
Select
PDCD6 / ALG-2 Rabbit anti-Human Polyclonal (aa32-191) (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$329; 200 µl/$381; 500 µl/$550; 1 ml/$654; 2 ml/$890; 5 ml/$1,487
PDCD6 / ALG-2 Antibody - Western blot of PDCD6 / ALG-2 antibody.
Select
PDCD6 / ALG-2 Rabbit anti-Human Polyclonal (aa32-191) (FITC) Antibody
Human
WB
FITC Conjugated
100 µl/$362; 200 µl/$427; 500 µl/$666; 1 ml/$826; 2 ml/$1,067; 5 ml/$1,892
PDCD6 / ALG-2 Antibody - Western blot of PDCD6 / ALG-2 antibody.
Select
PDCD6 / ALG-2 Rabbit anti-Human Polyclonal (aa32-191) (PE) Antibody
Human
WB
PE Conjugated
100 µl/$427; 200 µl/$519; 500 µl/$916; 1 ml/$1,084; 2 ml/$1,441; 5 ml/$2,703
PDCD6 / ALG-2 Antibody - Western blot of PDCD6 / ALG-2 antibody.
Select
PDCD6 / ALG-2 Rabbit anti-Human Polyclonal (aa32-191) (Cy3) Antibody
Human
WB
Cy3 Conjugated
100 µl/$427; 200 µl/$519; 500 µl/$916; 1 ml/$1,084; 2 ml/$1,441; 5 ml/$2,703
PDCD6 / ALG-2 Antibody - Western blot of PDCD6 / ALG-2 antibody.
Select
PDCD6 / ALG-2 Rabbit anti-Human Polyclonal (aa32-191) (APC, Cy7) Antibody
Human
WB
APC, Cy7 Conjugated
100 µl/$535; 200 µl/$714; 500 µl/$1,236; 1 ml/$1,545; 2 ml/$2,163; 5 ml/$4,053
PDCD6 / ALG-2 Antibody - Immunohistochemistry of paraffin-embedded Human thyroid cancer using PDCD6 Polyclonal Antibody at dilution of 1:30.
Select
PDCD6 / ALG-2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
Select
PDCD6 / ALG-2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IP, WB
Unconjugated
100 µg/$331
Select
PDCD6 / ALG-2 Rabbit anti-Human Polyclonal (aa19-47) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
Select
PDCD6 / ALG-2 Rabbit anti-Human Polyclonal (aa19-47) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
PDCD6 / ALG-2 Rabbit anti-Human Polyclonal (aa19-47) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
PDCD6 / ALG-2 Rabbit anti-Human Polyclonal (aa19-47) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
Select
PDCD6 / ALG-2 Rabbit anti-Human Polyclonal (aa19-47) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
Select
PDCD6 / ALG-2 Rabbit anti-Human Polyclonal (aa19-47) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
PDCD6 / ALG-2 Antibody
Select
PDCD6 / ALG-2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
100 µl/$332
PDCD6 / ALG-2 Antibody - Western blot analysis of PDCD6 using K562 whole lysates.
Select
PDCD6 / ALG-2 Rabbit anti-Human Polyclonal Antibody
Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
PDCD6 / ALG-2 Antibody - PDCD6 Antibody western blot of A549 cell line lysates (35 ug/lane). The PDCD6 antibody detected the PDCD6 protein (arrow).
Select
PDCD6 / ALG-2 Rabbit anti-Human Polyclonal (aa19-47) Antibody
Human
WB
Unconjugated
400 µl/$393
PDCD6 / ALG-2 Antibody - Western blot of lysate from mouse liver tissue lysate with PDCD6 Antibody. Antibody was diluted at 1:1000. A goat anti-rabbit IgG H&L (HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35 ug.
Select
PDCD6 / ALG-2 Rabbit anti-Human Polyclonal (aa103-137) Antibody
Mouse
WB
Unconjugated
400 µl/$393
Viewing 1-25 of 36 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).