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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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PDCD1LG2 / CD273 / PD‑L2 Antibody (Internal) LS‑C19687
PD-L2 antibody LS-C19687 is an unconjugated rabbit polyclonal antibody to PD-L2 (PDCD1LG2 / CD273) from human, mouse and rat. Validated for ELISA, IF, IHC and WB.
Catalog
Size
Price
LS-C19687-100
100 µg (1 mg/ml)
Unavailable

Popular PDCD1LG2 / CD273 / PD-L2 Products

Antibody
Species: Human
Applications: IHC, IHC - Frozen, Flow Cytometry
Surface staining of B7-DC transfected cells with anti-mouse B7-DC (TY25) PE. Appropriate isotype controls were used (open histogram). Total viable cells were used for analysis.
Species: Mouse
Applications: IHC, IHC - Frozen, Western blot, Immunoprecipitation, Flow Cytometry
Antibody
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, Western blot
Antibody
Species: Human
Applications: Flow Cytometry
IHC of paraffin-embedded Human tonsil using anti-PDCD1LG2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).
Species: Human
Applications: IHC, IHC - Paraffin, Western blot

Product Description

PD-L2 antibody LS-C19687 is an unconjugated rabbit polyclonal antibody to PD-L2 (PDCD1LG2 / CD273) from human, mouse and rat. Validated for ELISA, IF, IHC and WB.
About PDCD1LG2 / CD273 / PD-L2
Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production. Q9BQ51 NM_025239 NP_079515.2

PDCD1LG2 Antibody, B7 dendritic cell molecule Antibody, B7-DC Antibody, B7DC Antibody, BA574F11.2 Antibody, CD273 Antibody, Btdc Antibody, CD273 antigen Antibody, PD-L2 Antibody, PDCD1 ligand 2 Antibody, PD-1-ligand 2 Antibody, Programmed death ligand 2 Antibody, Butyrophilin B7-DC Antibody, PD-1 ligand 2 Antibody, PDCD1L2 Antibody, PDL2 Antibody


Specifications

Target
Human PDCD1LG2 / CD273 / PD-L2
Host
Rabbit
Reactivity
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC (2.5 µg/ml)
  • Immunofluorescence (20 µg/ml)
  • Western blot
  • ELISA
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Blocking Peptide
LS-E30320 - Liquid - 50 µg - $145.00
Immunizing peptide used to generate LS-C19687. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
Internal
Presentation
PBS, 0.02% sodium azide.
Storage
Store at 4°C for 3 months and -20°C, stable for up to 1 year. Avoid repeated freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Immunohistochemistry

Immunohistochemistry of PDL-2 in mouse brain tissue with PDL-2 antibody at 2.5 ug/ml.
Immunohistochemistry of PDL-2 in mouse brain tissue with PDL-2 antibody at 2.5 ug/ml.

Immunofluorescence

Immunofluorescence of PDL-2 in Mouse Brain cells with PDL-2 antibody at 20 ug/ml.
Immunofluorescence of PDL-2 in Mouse Brain cells with PDL-2 antibody at 20 ug/ml.

Western blot

Western blot of PDL-2 in Raji cell lysate with PDL-2 antibody at (A) 0.5, (B) 1 and (C) 2 ug/ml.
Western blot of PDL-2 in Raji cell lysate with PDL-2 antibody at (A) 0.5, (B) 1 and (C) 2 ug/ml.

Immunohistochemistry

Immunohistochemistry of PDL-2 in mouse brain tissue with PDL-2 antibody at 2.5 ug/ml.
Immunohistochemistry of PDL-2 in mouse brain tissue with PDL-2 antibody at 2.5 ug/ml.

Immunofluorescence

Immunofluorescence of PDL-2 in Mouse Brain cells with PDL-2 antibody at 20 ug/ml.
Immunofluorescence of PDL-2 in Mouse Brain cells with PDL-2 antibody at 20 ug/ml.

Western blot

Western blot of PDL-2 in Raji cell lysate with PDL-2 antibody at (A) 0.5, (B) 1 and (C) 2 ug/ml.
Western blot of PDL-2 in Raji cell lysate with PDL-2 antibody at (A) 0.5, (B) 1 and (C) 2 ug/ml.

Immunohistochemistry

Immunohistochemistry of PDL-2 in mouse brain tissue with PDL-2 antibody at 2.5 ug/ml.
Immunohistochemistry of PDL-2 in mouse brain tissue with PDL-2 antibody at 2.5 ug/ml.

Immunofluorescence

Immunofluorescence of PDL-2 in Mouse Brain cells with PDL-2 antibody at 20 ug/ml.
Immunofluorescence of PDL-2 in Mouse Brain cells with PDL-2 antibody at 20 ug/ml.

Western blot

Western blot of PDL-2 in Raji cell lysate with PDL-2 antibody at (A) 0.5, (B) 1 and (C) 2 ug/ml.
Western blot of PDL-2 in Raji cell lysate with PDL-2 antibody at (A) 0.5, (B) 1 and (C) 2 ug/ml.

Immunohistochemistry

Immunohistochemistry of PDL-2 in mouse brain tissue with PDL-2 antibody at 2.5 ug/ml.
Immunohistochemistry of PDL-2 in mouse brain tissue with PDL-2 antibody at 2.5 ug/ml.

Immunofluorescence

Immunofluorescence of PDL-2 in Mouse Brain cells with PDL-2 antibody at 20 ug/ml.
Immunofluorescence of PDL-2 in Mouse Brain cells with PDL-2 antibody at 20 ug/ml.

Western blot

Western blot of PDL-2 in Raji cell lysate with PDL-2 antibody at (A) 0.5, (B) 1 and (C) 2 ug/ml.
Western blot of PDL-2 in Raji cell lysate with PDL-2 antibody at (A) 0.5, (B) 1 and (C) 2 ug/ml.


Requested From: 
Date Requested: 6/18/2018

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