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Anti-PDCD1LG2 / CD273 / PD-L2 Antibody (FITC) LS-C44894

Note: This antibody replaces LS-C57987
Catalog Size Price
LS-C44894-100 100 µg (0.1 mg/ml) Unavailable

Most Popular PDCD1LG2 / CD273 / PD-L2 Antibodies

Anti-PDCD1LG2 / CD273 / PD-L2 Antibody (clone TY25) LS-C107118
Rat Monoclonal [clone TY25] (IgG2a,k) to Mouse PDCD1LG2 / CD273 / PD-L2
Mouse
IHC - Frozen, Western blot, Immunoprecipitation, Flow Cytometry
Unconjugated
Flow Cytometry Image
Anti-PDCD1LG2 / CD273 / PD-L2 Antibody LS-C121161
Rabbit Polyclonal (IgG) to Human PDCD1LG2 / CD273 / PD-L2
Human, Mouse, Rat
IHC - Paraffin, Western blot
Unconjugated
Anti-PDCD1LG2 / CD273 / PD-L2 Antibody (aa20-219) LS-C150224
Goat Polyclonal (IgG) to Mouse PDCD1LG2 / CD273 / PD-L2
Mouse
IHC, Western blot, Flow Cytometry, ELISA
Unconjugated
Immunohistochemistry Image
Anti-PDCD1LG2 / CD273 / PD-L2 Antibody (clone 8G8) LS-C340014
Mouse Monoclonal [clone 8G8] (IgG1) to Human PDCD1LG2 / CD273 / PD-L2
Human
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-PDCD1LG2 / CD273 / PD-L2 Antibody (clone ANC8D12) LS-C357679
Mouse Monoclonal [clone ANC8D12] (IgG2a,k) to Human PDCD1LG2 / CD273 / PD-L2
Human
Flow Cytometry, ELISA, Blocking
Unconjugated
Flow Cytometry Image

100% Guaranteed
Rat Monoclonal (IgG2a) to Mouse PDCD1LG2 / CD273 / PD-L2
Mouse
IHC - Frozen, Immunoprecipitation, Flow Cytometry
FITC Conjugated

Details

Mouse PDCD1LG2 / CD273 / PD-L2
Rat
Mouse (tested or 100% immunogen sequence identity)
IgG2a Monoclonal
Fluorescein
Protein G purified
Unmodified

Applications

  • IHC - Frozen
  • Immunoprecipitation
  • Flow Cytometry (1:1 - 1:5)

Specificity and Use

B7-DC transfected RAW264.7 cells.
Recognizes mouse CD273, a 42kD member of the B7 family, otherwise known as B7-dendritic cell (B7-DC), or programmed death ligand-2 (PD-L2). The expression of CD273 is restricted to a subpopulation of dendritic cells (DCs), and DCs and macrophages that have been stimulated with interferon gamma, GM-CSF or IL-4. CD273 has been identified as a ligand for PD-1(CD279), along with another B7 family member B7-H1 (CD279). Studies suggest that both CD273 and B7-H1 co-stimulate or inhibit T cell proliferation and cytokine production. Antibodies produced by clone TY25 are reported to block the binding of CD273 (B7-DC) to its receptor. XXX recommend the use of MCA2465EL for functional studies.
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul. The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity Fc receptors.

Packaging

PBS, pH 7.4, 0.09% sodium azide, 1% BSA.
For research use only.

About PDCD1LG2 / CD273 / PD-L2

Q9BQ51 NM_025239 NP_079515.2

PDCD1LG2 Antibody, B7 dendritic cell molecule Antibody, B7-DC Antibody, B7DC Antibody, BA574F11.2 Antibody, CD273 Antibody, Btdc Antibody, CD273 antigen Antibody, PD-L2 Antibody, PDCD1 ligand 2 Antibody, PD-1-ligand 2 Antibody, Programmed death ligand 2 Antibody, Butyrophilin B7-DC Antibody, PD-1 ligand 2 Antibody, PDCD1L2 Antibody, PDL2 Antibody

Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.

Requested From: 
Date Requested: 8/17/2017

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