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Anti-PDCD1LG2 / CD273 / PD-L2 Antibody (aa20-219) LS-C150224

Ordering

Wt. Vol. Conc. Price
100 µg - - $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular PDCD1LG2 / CD273 / PD-L2 Antibodies

Anti-PDCD1LG2 / CD273 / PD-L2 Antibody (clone 8G8) LS-C340014
Mouse Monoclonal [clone 8G8] (IgG1) to Human PDCD1LG2 / CD273 / PD-L2
Human
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-PDCD1LG2 / CD273 / PD-L2 Antibody (FITC) LS-C128028
Mouse Monoclonal (IgG1) to Human PDCD1LG2 / CD273 / PD-L2
Human
Flow Cytometry
FITC Conjugated

100% Guaranteed 100% Guaranteed
Goat Polyclonal (IgG) to Mouse PDCD1LG2 / CD273 / PD-L2
Mouse
IHC, Western blot, Flow Cytometry, ELISA
Unconjugated

Details

Mouse PDCD1LG2 / CD273 / PD-L2
Goat
Mouse (tested or 100% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • IHC (5 - 15 µg/ml)
  • Western blot (0.1 µg/ml)
  • Flow Cytometry
  • ELISA (4 µg/ml)

Specificity and Use

PDCD1LG2 / CD273 / PD-L2 antibody was raised against mouse myeloma cell line NS0-derived recombinant mouse PDL2 Leu20-Arg219 Accession # Q9 WUL5.
aa20-219
Detects mouse PDL2 in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 20% cross-reactivity with.
Western Blot, 0.1 µg/ml, Recombinant Mouse PD-L2 Fc Chimera. Flow Cytometry, 2.5 µg/106 cells, RAW 264.7 mouse monocyte/macrophage cell line treated with LPS. Immunohistochemistry, 5-15 µg/ml, Blockade of Receptor-ligand Interaction, In a functional ELISA, 1-4 µg/ml of this antibody will block 50% of the binding of 1 µg/ml of Recombinant Mouse. PD-1 to immobilized Recombinant Mouse PD-L2 Fc Chimera coated at 1 µg/ml (100 ul/well). At 30 µg/ml, this antibody will block >90% of the binding.

Packaging

Lyophilized from 0.2 um filtered solution in PBS, trehalose
Sterile PBS. Resuspend to 500 ul
Long term: -20°C; Short term: +4°C; Avoid freeze-thaw cycles.
For research use only.

About PDCD1LG2 / CD273 / PD-L2

Q9BQ51 NM_025239 NP_079515.2

PDCD1LG2 Antibody, B7 dendritic cell molecule Antibody, B7-DC Antibody, B7DC Antibody, BA574F11.2 Antibody, CD273 Antibody, Btdc Antibody, CD273 antigen Antibody, PD-L2 Antibody, PDCD1 ligand 2 Antibody, PD-1-ligand 2 Antibody, Programmed death ligand 2 Antibody, Butyrophilin B7-DC Antibody, PD-1 ligand 2 Antibody, PDCD1L2 Antibody, PDL2 Antibody

Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.

Immunohistochemistry

Immunohistochemistry
PD-L2 in Mouse Thymus. PD-L2 was detected in perfusion fixed frozen sections of mouse thymus using 15 ug/ml Goat Anti-Mouse PD-L2 Antigen Affinity-purified Polyclonal Antibody overnight at 4°C. Tissue was stained with Anti-Goat HRP-DAB (brown) and counterstained with hematoxylin (blue).
 

Requested From: United States
Date Requested: 12/8/2016

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