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Anti-PC / Pyruvate Carboxylase Antibody (aa930-1050, DY550) LS-C143470

Ordering

Wt. Vol. Conc. Price
- 100 µl - $365
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular PC / Pyruvate Carboxylase Antibodies

Anti-PC / Pyruvate Carboxylase Antibody (aa886-899) IHC-plus™ LS-B2457
Goat Polyclonal to Human PC / Pyruvate Carboxylase
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Hamster, Horse, Pig, Rabbit
IHC - Paraffin, Western blot, ELISA
Unconjugated
Immunohistochemistry Image
Anti-PC / Pyruvate Carboxylase Antibody (aa53-82) LS-C163402
Rabbit Polyclonal to Human PC / Pyruvate Carboxylase
Human, Mouse
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-PC / Pyruvate Carboxylase Antibody LS-C285798
Rabbit Polyclonal (IgG) to Yeast PC / Pyruvate Carboxylase
Yeast
ELISA
Unconjugated

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Human PC / Pyruvate Carboxylase
Human
IHC, IHC - Paraffin, ICC, Immunofluorescence, Western blot (applications tested for the base form of this product only)
DY550 Conjugated

Details

Human PC / Pyruvate Carboxylase
Rabbit
Human (tested or 100% immunogen sequence identity)
Rat, Bovine (at least 90% immunogen sequence identity)
Polyclonal
DyLight 550. Also available Unconjugated or conjugated with Biotin, DY650, DY488.
Affinity purified
Unmodified

Applications

  • IHC (1:200)
  • IHC - Paraffin
  • ICC (1:50 - 1:100)
  • Immunofluorescence (1:50 - 1:100)
  • Western blot (1:1000)
  • (applications tested for the base form of this product only)

Specificity and Use

PC / Pyruvate Carboxylase antibody was raised against a genomic peptide made to an internal region of the human Pyruvate Carboxylase protein (within residues 930-1050). [Swiss-Prot P11498]. Percent identity by BLAST analysis: Bovine, Porcine (96%); Rat (92%).
aa930-1050
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Packaging

50 mM sodium borate
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
For research use only.

About PC / Pyruvate Carboxylase

P11498 NM_000920 NP_000911.2

PC Antibody, PCB Antibody, Pyruvate carboxylase Antibody, Pyruvic carboxylase Antibody

PC / Pyruvate Carboxylase is pyruvate carboxylase, which requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency.

Immunohistochemistry

Immunohistochemistry
Immunohistochemistry: Pyruvate Carboxylase Antibody - Analysis of Pyruvate Carboxylase in mouse kidney and mouse fat. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Immunocytochemistry

Immunocytochemistry
Immunocytochemistry/Immunofluorescence: Pyruvate Carboxylase Antibody - Immunocytochemistry of Pyruvate Carboxylase in HeLa. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Western blot
Western Blot: Pyruvate Carboxylase Antibody - Analysis of Pyruvate Carboxylase in A. Human liver extracts and B. Mouse liver extracts. This image was taken for the unconjugated form of this product. Other forms have not been tested.
 

Requested From: United States
Date Requested: 12/9/2016

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