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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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PAX2 Antibody (aa188‑385) LS‑C9505 Best Seller
PAX2 antibody LS-C9505 is an unconjugated rabbit polyclonal antibody to PAX2 from human, mouse, rat and other species. Validated for ELISA, IHC, IP and WB. Cited in 1 publication.
Antibody
Catalog
Size
Price
LS-C9505-100
100 µg (0.25 mg/ml)
$635

Popular PAX2 Products

Anti-PAX2 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4389 concentration 5 ug/ml.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, ELISA
Anti-PAX2 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2450 dilution 1:50.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, ELISA
PAX2 antibody LS-C31501 was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Monkey, Bat, Bovine, Dog, Guinea pig, Horse, Pig, Rabbit, Sheep, Chicken, Zebrafish
Applications: IHC, IHC - Paraffin, Western blot
Immunofluorescence analysis of A549 cell using PAX2 antibody. Blue: DAPI for nuclear staining.
Species: Human, Mouse
Applications: Immunofluorescence, Western blot

Product Description

PAX2 antibody LS-C9505 is an unconjugated rabbit polyclonal antibody to PAX2 from human, mouse, rat and other species. Validated for ELISA, IHC, IP and WB. Cited in 1 publication.

Specifications

Target
Mouse PAX2
Synonyms
PAX2, Paired box homeotic gene 2, Paired box protein Pax-2, PAPRS, Paired box 2, Paired box gene 2
Host
Rabbit
Reactivity
Mouse, Human, Rat, Xenopus (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Protein A purified
Modifications
Unmodified
Applications
  • IHC (5 µg/ml)
  • Western blot (1 µg/ml)
  • Immunoprecipitation
  • ELISA (0.1 - 1 µg/ml)
  • (applications tested for the base form of this product only)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
PAX2 antibody was raised against a GST-Pax-2 fusion protein derived from the C-terminal domain (aa188-385) of the murine Pax-2 protein (1).
Epitope
aa188-385
Specificity
Recognizes Pax-2 protein and does not cross-react with other Pax family members. The major epitopes are located between aa204-373 of mouse Pax-2. Two proteins are detected in mouse embryonic kidney lysates with this antibody: a major band at 46kD (Pax-2b) and a minor band at 48kD (Pax-2a). Reactivity: ELISA: Immunogen; WB: Xenopus, zebrafish, embryonic mouse kidney, human Wilms' tumors; IHC (frozen): Rat, Xenopus, zebrafish, human Wilms' tumor, mouse; IHC (paraffin): Human Wilms' tumor, mouse; IP: Embryonic mouse kidney.
Usage
Suitable for use in ELISA, Immunoprecipitation, Western Blot and Immunohistochemistry. ELISA: 0.1-1 ug/ml. Western Blot: 1 ug/ml. Immunohistochemistry: 5 ug/ml (whole mount staining).
Presentation
PBS, pH 7.4, 0.09% Sodium Azide
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
About PAX2
PAX2 encodes paired box gene 2, one of many human homologues of the Drosophila melanogaster gene prd. The central feature of this transcription factor gene family is the conserved DNA-binding paired box domain. PAX2 is believed to be a target of transcriptional supression by the tumor suppressor gene WT1. Mutations within PAX2 have been shown to result in optic nerve colobomas and renal hypoplasia. Alternative splicing of this gene results in multiple transcript variants. Q02962 NM_003987 NP_003978.2


Publications (1)

1
Hyperoxia causes reduced density of retinal astrocytes in the central avascular zone in the mouse model of oxygen-induced retinopathy. Bucher F, Stahl A, Agostini HT, Martin G. Molecular and cellular neurosciences. 2013 Sep;56:225-33. [Full Text Article] [PubMed:23756201]

Customer Reviews (0)


Requested From: United States
Date Requested: 10/18/2018

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