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PAWR / PAR4

PRKC, apoptosis, WT1, regulator

Pro-apoptopic protein capable of selectively inducing apoptosis in cancer cells, sensitizing the cells to diverse apoptotic stimuli and causing regression of tumors in animal models. Induces apoptosis in certain cancer cells by activation of the Fas prodeath pathway and coparallel inhibition of NF-kappa-B transcriptional activity. Inhibits the transcriptional activation and augments the transcriptional repression mediated by WT1. Down-regulates the anti-apoptotic protein BCL2 via its interaction with WT1. Seems also to be a transcriptional repressor by itself. May be directly involved in regulating the amyloid precursor protein (APP) cleavage activity of BACE1.

Gene Name: PRKC, apoptosis, WT1, regulator
Synonyms: PAWR, PAR4, WT1-interacting protein, Par-4, Transcriptional repressor PAR4
Target Sequences: NM_002583 NP_002574.2 Q96IZ0

☰ Filters
Antibodies (35)
ELISA Kits (6)
Proteins (4)
Cell-Based (1)
Over-Expression Lysate (2)
Primary (35)
Recombinant (2)
Sandwich (4)
Sandwich CLIA (1)
PAWR / PAR4 (45)
Human (40)
Mouse (17)
Rat (18)
Bovine (1)
Chicken (1)
Dog (7)
Guinea pig (3)
Horse (3)
Monkey (7)
Pig (6)
Rabbit (3)
IHC (27)
IHC-P (13)
WB (33)
ELISA (10)
IF (2)
IP (2)
Peptide-ELISA (3)
rabbit (32)
mouse (3)
Product Group
IHCPlus (3)
IgG (19)
IgG1 (3)
monoclonal mc (3)
polyclonal pc (32)
3G9H7 (1)
3G9H7,4H12E9 (1)
12 x 8-Well Microstrips (1)
96-Well Microplate (1)
96-Well Strip Plate (4)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
Unconjugated (29)
aa166-215 (4)
aa212-261 (4)
260-340 aa, C-terminal (1)
Amino Acid: 1-330 (1)
Asp313 (1)
C-Terminus (1)
Internal (1)
aa1-15 (1)
aa225-275 (1)
aa290-340 (1)
aa291-340 (1)
No (45)
Adherent Cell Cultures (1)
Cell Lysates (2)
Plasma (3)
Serum (3)
Tissue Homogenates (3)
GST, N-terminus (1)
Myc-DDK (Flag) (3)
Human (3)
293T Cells (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
PAWR / PAR4 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
25 - 1600 pg/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$958
PAWR / PAR4 Antibody - Anti-PAWR / PAR4 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
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PAWR / PAR4 Mouse anti-Human Monoclonal (3G9H7) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$460
PAWR / PAR4 Antibody - 1:100 staining human gastric tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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PAWR / PAR4 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
PAWR / PAR4 Antibody - Anti-PAWR / PAR4 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
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PAWR / PAR4 Rabbit anti-Human Polyclonal (aa291-340) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
100 µl/$515
PAWR / PAR4 Antibody - 1:100 staining human gastric tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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PAWR / PAR4 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
PAWR / PAR4 Antibody - Anti-PAWR / PAR4 antibody IHC of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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PAWR / PAR4 Rabbit anti-Human Polyclonal (aa1-15) Antibody
Human
IHC, IHC-P
Unconjugated
50 µl/$460
PAWR / PAR4 Antibody - Immunohistochemistry of paraffin-embedded Human colon cancer using PAWR Polyclonal Antibody at dilution of 1:60.
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PAWR / PAR4 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
PAWR / PAR4 Antibody - Immunohistochemistry (IHC) analysis of paraffin-embedded Human Brain (left) and breast carcinoma (right), showing cytoplasmic and membrane localization with DAB staining using PAR4 Monoclonal Antibody.
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PAWR / PAR4 Mouse anti-Human Monoclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µg/$332; 100 µg/$404; 200 µg/$505
PAWR / PAR4 Antibody - PAWR / PAR4 antibody ARP32735_T100-NP_002574-PAWR (PRKC, apoptosis, WT1, regulator) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PAWR / PAR4 Rabbit anti-Human Polyclonal (aa212-261) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$397
PAWR / PAR4 Antibody - PAWR / PAR4 antibody ARP32735_T100-NP_002574-PAWR (PRKC, apoptosis, WT1, regulator) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
PAWR / PAR4 Rabbit anti-Human Polyclonal (aa212-261) (HRP) Antibody
Dog, Pig, Horse, Human, Monkey
IHC, IHC-P, WB
HRP Conjugated
100 µl/$442
PAWR / PAR4 Antibody - PAWR / PAR4 antibody ARP32735_T100-NP_002574-PAWR (PRKC, apoptosis, WT1, regulator) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
PAWR / PAR4 Rabbit anti-Human Polyclonal (aa212-261) (Biotin) Antibody
Dog, Pig, Horse, Human, Monkey
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$442
PAWR / PAR4 Antibody - PAWR / PAR4 antibody ARP32735_T100-NP_002574-PAWR (PRKC, apoptosis, WT1, regulator) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
PAWR / PAR4 Rabbit anti-Human Polyclonal (aa212-261) (FITC) Antibody
Dog, Pig, Horse, Human, Monkey
IHC, IHC-P, WB
FITC Conjugated
100 µl/$442
Select
PAWR / PAR4 Rabbit anti-Human Polyclonal (Internal) Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µg/$440; 100 µg/$480
Select
PAWR / PAR4 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$331
PAWR / PAR4 Antibody - Immunohistochemistry of paraffin-embedded human colon cancer tissue.
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PAWR / PAR4 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
PAWR / PAR4 Antibody - Western blot of PAR4 antibody
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PAWR / PAR4 Rabbit anti-Human Polyclonal (260-340 aa, C-terminal) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
PAWR / PAR4 Antibody - PAR4 Antibody in Immunohistochemistry (IHC)
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PAWR / PAR4 Mouse anti-Human Monoclonal (Amino Acid: 1-330) (3G9H7,4H12E9) Antibody
Human
IHC, WB
Unconjugated
100 µl/$541
PAWR / PAR4 Antibody
Select
PAWR / PAR4 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µl/$332
PAWR / PAR4 Antibody - Peptide - + Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using Prostate Apoptosis Response Protein-4 antibody.
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PAWR / PAR4 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100 µg/$357
PAWR / PAR4 Antibody - PAWR / PAR4 antibody ARP32062_P050-NP_002574-PAWR (PRKC, apoptosis, WT1, regulator) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human muscle.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PAWR / PAR4 Rabbit anti-Human Polyclonal (aa166-215) Antibody
Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$424
PAWR / PAR4 Antibody - IHC of Prostate Apoptosis Response protein-4 (D313) pAb in paraffin-embedded human lung carcinoma tissue.
Select
PAWR / PAR4 Rabbit anti-Human Polyclonal (Asp313) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$321; 100 µl/$403
PAWR / PAR4 Antibody - Immunohistochemical analysis of PAWR staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Select
PAWR / PAR4 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Chicken, Bovine, Mouse, Dog, Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$299
Select
PAWR / PAR4 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
50 µl/$356; 100 µl/$461
Select
PAWR / PAR4 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
50 µg/$305; 100 µg/$357
Select
PAWR / PAR4 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
100 µl/$386
Viewing 1-25 of 45 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).