Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. May link the DNA damage surveillance network to the mitotic fidelity checkpoint.
IHC of paraffin-embedded OVCA using PARP3 antibody at 1:100 dilution.
Immunofluorescence of paraformaldehyde-fixed HeLa using PARP3 antibody at 1:500 dilution.
PARP3 antibody detects PARP3 protein by Western blot analysis. A. 30 ug A431 whole cell lysate/extract. B. 30 ug HeLa whole cell lysate/extract. C. 30 ug A375 whole cell lysate/extract. 7.5 % SDS-PAGE. PARP3 antibody dilution:1:1000
PARP3 antibody detects PARP3 protein by Western blot analysis. A. 30 ug PC-12 whole cell lysate/extract. 7.5 % SDS-PAGE. PARP3 antibody dilution:1:1000
Sample (50 ug of whole cell lysate). A: mouse heart. 7.5% SDS PAGE. PARP3 antibody diluted at 1:1000.