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PARP1 Antibody (phospho‑Ser274) LS‑C158536
PARP1 antibody LS-C158536 is an unconjugated rabbit polyclonal antibody to human PARP1. Validated for DB.
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Species:
Human, Monkey, Dog, Hamster, Rabbit
Applications:
ICC, Western blot, Immunoprecipitation, ELISA
Species:
Human, Mouse, Rat
Applications:
IHC, IHC - Paraffin, Western blot
Species:
Human, Mouse, Rat
Applications:
IHC, IHC - Paraffin, Western blot
Species:
Human, Mouse, Rat, Hamster, Xenopus, Drosophila
Applications:
IHC, IHC - Paraffin, IHC - Frozen, Western blot, Immunoprecipitation, ELISA
Species:
Applications:
ICC, Western blot, Immunoprecipitation, ELISA
Product Description
PARP1 antibody LS-C158536 is an unconjugated rabbit polyclonal antibody to human PARP1. Validated for DB.
About PARP1
Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. Mediates the poly(ADP-ribosyl)ation of APLF and CHFR.
P09874
NM_001618
NP_001609.2
PARP1 Antibody, ADPRT Antibody, ADP-ribosyltransferase NAD(+) Antibody, Adp-ribosyltransferase Antibody, ADPRT1 Antibody, ARTD1 Antibody, ADPRT 1 Antibody, Poly(ADP-ribose) synthetase Antibody, Poly(ADP-ribosyl)transferase Antibody, PARP Antibody, Poly [ADP-ribose] polymerase 1 Antibody, PADPRT-1 Antibody, PARP-1 Antibody, Poly (ADP-ribose) polymerase 1 Antibody, Poly(ADP-ribose) polymerase Antibody, Poly[ADP-ribose] synthase 1 Antibody, PPOL Antibody
Specifications
Target
Human PARP1
Host
Rabbit
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Protein A purified
Modifications
Unmodified
Applications
- Dot Blot (1:500)
Blocking Peptide
LS-E7537 - Lyophilized - 100 µg - $230.00
Immunizing peptide used to generate LS-C158536. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Immunizing peptide used to generate LS-C158536. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
pSer274
Specificity
This PARP1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S274 of human PARP1.
Presentation
PBS, 0.09% sodium azide
Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.
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Images
Dot Blot
Dot blot of Phospho-PARP1-S274 Antibody Phospho-specific antibody on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.6ug per ml.
Dot Blot
Dot blot of Phospho-PARP1-S274 Antibody Phospho-specific antibody on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.6ug per ml.
Dot Blot
Dot blot of Phospho-PARP1-S274 Antibody Phospho-specific antibody on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.6ug per ml.
Dot Blot
Dot blot of Phospho-PARP1-S274 Antibody Phospho-specific antibody on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.6ug per ml.
Requested From:
Date Requested: 6/19/2018
Date Requested: 6/19/2018
