Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone 341/7H (PAR3)] (IgG2a) to Parainfluenza Virus 3
Parainfluenza Virus 3
Parainfluenza Virus (tested or 100% immunogen sequence identity)
IgG2a Monoclonal [341/7H (PAR3)]
Specificity and Use
Parainfluenza 3 hemagglutinin protein.
Recognizes an epitope within the hemagglutinin-neuraminidase (HN) protein of parainfluenza virus 3 (HPIV-3), an enveloped single-stranded RNA virus of the Paramyxoviridae family. Parainfluenza viruses are genetically and antigenically divided into the four types HPIV1-4, with HPIV-1, -2 and -3 being major causative agents of lower respiratory infections in the young and immunologically vulnerable. The HN protein of all HPIV, is a 69-82kD surface glycoprotein which mediates the attachment of the virus to the host cell, through binding to cell surface sialic acid-containing receptors. The receptor-cleaving neuraminidase activity of HN is essential for further infection by HPIV, by ensuring the release of progeny virions. Can be used in IFA typing studies in conjunction for the detection of parainfluenza virus types 1, 2 and 3.