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PAPSS 1

3'-phosphoadenosine 5'-phosphosulfate synthase 1

Bifunctional enzyme with both ATP sulfurylase and APS kinase activity, which mediates two steps in the sulfate activation pathway. The first step is the transfer of a sulfate group to ATP to yield adenosine 5'-phosphosulfate (APS), and the second step is the transfer of a phosphate group from ATP to APS yielding 3'-phosphoadenylylsulfate (PAPS: activated sulfate donor used by sulfotransferase). In mammals, PAPS is the sole source of sulfate; APS appears to be only an intermediate in the sulfate-activation pathway. Also involved in the biosynthesis of sulfated L-selectin ligands in endothelial cells.

Gene Name: 3'-phosphoadenosine 5'-phosphosulfate synthase 1
Synonyms: PAPSS1, ATPSK1, PAPS synthase 1, SK1, PAPSS 1, SK 1, Sulfurylase kinase 1, Paps synthetase, PAPSS
Target Sequences: NM_005443 NP_005434.4 O43252

☰ Filters
Antibodies (11)
Proteins (8)
Over-Expression Lysate (2)
Primary (11)
Recombinant (6)
PAPSS 1 (19)
Human (11)
Mouse (2)
Rat (1)
IHC (2)
IHC-P (1)
WB (10)
ELISA (8)
ICC (1)
IF (1)
IP (1)
rabbit (11)
IgG (10)
polyclonal pc (11)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
PE Conjugated (1)
Unconjugated (6)
aa592-624 (7)
No (19)
6His, C-terminus (2)
GST (1)
GST, N-terminus (1)
His (1)
Myc-DDK (Flag) (3)
Human (7)
293T Cells (1)
E. coli (1)
HEK 293 Cells (2)
Human Cells (1)
Mammalian Cells (1)
Wheat Germ Extract (2)
Purified (2)
Low endotoxin level (2)
PAPSS 1 Antibody - Immunochemical staining of human PAPSS1 in human bronchi with rabbit polyclonal antibody at 1:500 dilution, formalin-fixed paraffin embedded sections.
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PAPSS 1 Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF, IHC-P, IP, WB
Unconjugated
100 µl/$412
Select
PAPSS 1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$341
PAPSS 1 Antibody - Immunohistochemistry of paraffin-embedded Human gastric cancer using PAPSS1 Polyclonal Antibody at dilution of 1:40.
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PAPSS 1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
Select
PAPSS 1 Rabbit anti-Human Polyclonal (aa592-624) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
Select
PAPSS 1 Rabbit anti-Human Polyclonal (aa592-624) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
PAPSS 1 Rabbit anti-Human Polyclonal (aa592-624) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
PAPSS 1 Rabbit anti-Human Polyclonal (aa592-624) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
Select
PAPSS 1 Rabbit anti-Human Polyclonal (aa592-624) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
Select
PAPSS 1 Rabbit anti-Human Polyclonal (aa592-624) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
PAPSS 1 Antibody - Western blot of anti-PAPSS1 Antibody (C-term A607) in A2058 cell line lysates (35 ug/lane). PAPSS1(arrow) was detected using the purified antibody.
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PAPSS 1 Rabbit anti-Human Polyclonal (aa592-624) Antibody
Human
WB
Unconjugated
400 µl/$393
PAPSS 1 Antibody - Western blot analysis of extracts of various cell lines, using PAPSS1 antibody at 1:3000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 90s.
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PAPSS 1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
PAPSS 1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
70.7 kDa
100 µg/$710
PAPSS 1 Protein - 12.5% SDS-PAGE of human PAPSS1 stained with Coomassie Blue
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Wheat Germ Extract
GST
94.9 kDa
10 µg/$479; 25 µg/$670
PAPSS 1 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
PAPSS 1 Protein - Purified recombinant protein PAPSS1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
70.7 kDa
20 µg/$1,107
PAPSS 1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
70.7 kDa
20 µg/$215
PAPSS 1 Protein
Select
E. coli
His
100 µg/$411; 500 µg/$985; 20 µg/$276
Select
Mammalian Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
71.9 kDa
10 µg/$344; 50 µg/$584
Select
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
71.9kD
10 µg/$321; 50 µg/$534; 500 µg/$1,585; 1 mg/$2,353
Viewing 1-19 of 19 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).