Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
(tested or 100% immunogen sequence identity)
Protein A/G purified
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
PAPPA / PAPP-A antibody was raised against purified human PAPP-A.
Specific for native human PAPP-A. The epitope is different from that of clone 6F174 and is located on the PAPP-A subunit of the heterotetramer. Detects only unreduced PAPP-A in Western Blot. In sandwich ELISA with a polyclonal antibody in coat reacts poorly with PAPP-A in third trimester serum.
Suitable for use in ELISA, Western Blot, and Immunohistochemistry. ELISA: 1:20.
PBS, pH 7.2, 15 mM Sodium Azide
Short term: 4°C; Long term: Add glycerol (40-50%) -20°C.
Metalloproteinase which specifically cleaves IGFBP-4 and IGFBP-5, resulting in release of bound IGF. Cleavage of IGFBP-4 is dramatically enhanced by the presence of IGF, whereas cleavage of IGFBP-5 is slightly inhibited by the presence of IGF.