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PAPPA / PAPP-A

pregnancy-associated plasma protein A, pappalysin 1

Metalloproteinase which specifically cleaves IGFBP-4 and IGFBP-5, resulting in release of bound IGF. Cleavage of IGFBP-4 is dramatically enhanced by the presence of IGF, whereas cleavage of IGFBP-5 is slightly inhibited by the presence of IGF.

Gene Name: pregnancy-associated plasma protein A, pappalysin 1
Family/Subfamily: Protease , Metallopeptidase M43
Synonyms: PAPPA, DIPLA1, IGF-dependent IGFBP-4 protease, PAPPA1, PAPA, PAPP-A, Pappalysin-1, ASBABP2, IGFBP-4ase
Target Sequences: NM_002581 NP_002572.2 Q13219

Publications (1)

1
Persistent DNA Damage and Senescence in the Placenta Impacts Developmental Outcomes of Embryos. Vijay Pratap Singh, Sean McKinney, Jennifer L Gerton. The Breast : official journal of the European Society of Mastology. 2020 Aug;54:333-347.e7. [Full Text Article] [PubMed:32800293]

☰ Filters
Antibodies (95)
ELISA Kits (20)
Proteins (6)
Competitive EIA (1)
Custom (1)
Primary (95)
Recombinant (6)
Sandwich (16)
Sandwich CLIA (2)
PAPPA / PAPP-A (121)
Human (95)
Mouse (17)
Rat (2)
Chicken (1)
Monkey (1)
Porcine (1)
Rabbit (1)
IHC (8)
IHC-P (4)
WB (60)
ELISA (51)
ICC (2)
IP (34)
rabbit (42)
mouse (53)
Product Group
IHCPlus (2)
IgG (12)
IgG1,k (2)
IgG2a (24)
IgG2b (18)
IgG2b,k (3)
monoclonal mc (53)
polyclonal pc (42)
1_1 (1)
1_24 (1)
10E1 (2)
10E2 (1)
10H9 (1)
11E4 (1)
1G3 (1)
3C8 (1)
4G11 (1)
5H9 (1)
7A6 (1)
12 x 8-Well Microstrips (2)
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96-Well Strip Plate (14)
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HRP Conjugated (11)
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Unconjugated (33)
aa244-501 (10)
aa1270-1558 (8)
aa317-532 (8)
aa999-1272 (8)
aa95-388 (1)
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GST, N-terminus (1)
His (3)
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Myc-DDK (Flag) (1)
Human (5)
Mouse (1)
E. coli (4)
HEK 293 Cells (1)
Wheat Germ Extract (1)
Select
PAPPA / PAPP-A Mouse anti-Human Monoclonal (1G3) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
PAPPA / PAPP-A ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$685
PAPPA / PAPP-A ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
78.13 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$782
PAPPA / PAPP-A Antibody - Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
PAPPA / PAPP-A Rabbit anti-Mouse Polyclonal (aa999-1272) Antibody
Mouse
IHC, IHC-P, WB
Unconjugated
50 µl/$460
Select
PAPPA / PAPP-A Mouse anti-Human Monoclonal (7A6) Antibody
Human
IP
Unconjugated
0.2 mg/$407; 0.5 mg/$487
Select
PAPPA / PAPP-A Mouse anti-Human Monoclonal (5H9) Antibody
Human
IP
Unconjugated
0.2 mg/$407; 0.5 mg/$487
PAPPA / PAPP-A Protein - Recombinant Pregnancy Associated Plasma Protein A By SDS-PAGE
Select
E. coli
His-GST, N-terminus
62.2 kDa
10 µg/$279; 50 µg/$430; 100 µg/$687; 200 µg/$857; 1 mg/$1,956; 500 µg/$1,499; 5 mg/$2,997; 2 mg/$2,142
Select
PAPPA / PAPP-A Mouse anti-Human Monoclonal (10E1) Antibody
Human
ELISA, IP, WB
Unconjugated
0.2 mg/$486
PAPPA / PAPP-A Antibody - PAPP A antibody IHC-paraffin: Human Placenta Tissue.
Select
PAPPA / PAPP-A Rabbit anti-Human Polyclonal (aa95-388) Antibody
Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
Select
PAPPA / PAPP-A Mouse anti-Human Monoclonal (HRP) Antibody
Human
ELISA, IP, WB
HRP Conjugated
100 µl/$1,085
Select
PAPPA / PAPP-A Mouse anti-Human Monoclonal (FITC) Antibody
Human
ELISA, IP, WB
FITC Conjugated
100 µl/$1,085
Select
PAPPA / PAPP-A Mouse anti-Human Monoclonal (APC) Antibody
Human
ELISA, IP, WB
APC Conjugated
100 µl/$1,085
Select
PAPPA / PAPP-A Mouse anti-Human Monoclonal (PE) Antibody
Human
ELISA, IP, WB
PE Conjugated
100 µl/$1,085
Select
PAPPA / PAPP-A Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
100 µg/$357
Select
PAPPA / PAPP-A Mouse anti-Human Monoclonal Antibody
Human
ELISA
Unconjugated
200 µg/$757
Select
PAPPA / PAPP-A Mouse anti-Human Monoclonal (4G11) Antibody
Human
IP
Unconjugated
0.2 mg/$407; 0.5 mg/$487
PAPPA / PAPP-A ELISA Kit
Select
Sandwich
96-Well Microplate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
PAPPA / PAPP-A ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$764
Select
PAPPA / PAPP-A Mouse anti-Human Monoclonal (1_1) Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µl/$1,090
Select
PAPPA / PAPP-A Mouse anti-Human Monoclonal (1_24) Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µl/$1,043
Select
PAPPA / PAPP-A Mouse anti-Human Monoclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µl/$1,090
PAPPA / PAPP-A Antibody - Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE), at a dilution of 1:100
Select
PAPPA / PAPP-A Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC, IHC-P
Unconjugated
60 µl/$460
PAPPA / PAPP-A Antibody - Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
PAPPA / PAPP-A Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC, IHC-P
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
Select
PAPPA / PAPP-A Mouse anti-Human Monoclonal (APC) Antibody
Human
ELISA, IP, WB
APC Conjugated
100 µl/$1,085
Select
PAPPA / PAPP-A Mouse anti-Human Monoclonal (PE) Antibody
Human
ELISA, IP, WB
PE Conjugated
100 µl/$1,085
Viewing 1-25 of 121 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).