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PAN2 / USP52

PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)

Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA when the poly(A) stretch is bound by poly(A)-binding protein (PABP), which is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1.

Gene Name: PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
Synonyms: PAN2, PYPAF4, Ubiquitin specific protease 52, USP52
Target Sequences: NM_001127460 NP_001120932.1 Q504Q3

☰ Filters
Antibodies (14)
Proteins (6)
Over-Expression Lysate (4)
Primary (14)
Recombinant (2)
PAN2 / USP52 (20)
Human (14)
Mouse (2)
IHC (2)
IHC-P (1)
WB (10)
ELISA (11)
IF (1)
IP (1)
rabbit (14)
IgG (13)
polyclonal pc (14)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (1)
Unconjugated (6)
aa860-888 (7)
aa1-50 (1)
No (20)
GST, N-terminus (1)
Myc-DDK (Flag) (5)
Human (4)
293T Cells (2)
HEK 293 Cells (3)
Wheat Germ Extract (1)
PAN2 / USP52 Antibody - Immunohistochemistry of paraffin-embedded human liver tissue at dilution of 1:100
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PAN2 / USP52 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
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PAN2 / USP52 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
Select
PAN2 / USP52 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
Select
PAN2 / USP52 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
Select
PAN2 / USP52 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$341
Select
PAN2 / USP52 Rabbit anti-Human Polyclonal (aa860-888) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
Select
PAN2 / USP52 Rabbit anti-Human Polyclonal (aa860-888) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
PAN2 / USP52 Rabbit anti-Human Polyclonal (aa860-888) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
PAN2 / USP52 Rabbit anti-Human Polyclonal (aa860-888) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
Select
PAN2 / USP52 Rabbit anti-Human Polyclonal (aa860-888) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
Select
PAN2 / USP52 Rabbit anti-Human Polyclonal (aa860-888) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
PAN2 / USP52 Antibody - Detection of human and mouse PAN2/USP52 by western blot. Samples: Whole cell lysate (50 µg) from HeLa, HEK293T, Jurkat, mouse TCMK-1, and mouse NIH 3T3 cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-PAN2/USP52 antibody used for WB at 0.1 µg/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.
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PAN2 / USP52 Rabbit anti-Human Polyclonal (aa1-50) Antibody
Mouse, Human
IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
PAN2 / USP52 Antibody - PAN2 Antibody western blot of ZR-75-1 cell line lysates (35 ug/lane). The PAN2 antibody detected the PAN2 protein (arrow).
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PAN2 / USP52 Rabbit anti-Human Polyclonal (aa860-888) Antibody
Human
WB
Unconjugated
400 µl/$393
PAN2 / USP52 Antibody - Western blot analysis of extracts of various cell lines, using PAN2 antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 15s.
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PAN2 / USP52 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
PAN2 / USP52 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
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293T Cells
Myc-DDK (Flag)
134.8 kDa
20 µg/$150
PAN2 / USP52 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
135.2 kDa
20 µg/$215
PAN2 / USP52 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
134.8 kDa
100 µg/$494
PAN2 / USP52 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
135.2 kDa
100 µg/$710
PAN2 / USP52 Protein - Purified recombinant protein PAN2 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
134.8 kDa
20 µg/$1,107
Viewing 1-20 of 20 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).