Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human, Bovine (tested or 100% immunogen sequence identity)
Western blot (1:500 - 1:1000)
Specificity and Use
PAK6 antibody was raised against fusion protein against amino acid 151-250 fragment from human PAK6.
Specific for PAK6. Species cross-reactivity: human and bovine.
Suitable for use in Western blot and Immunoprecipitation. Western Blot: 1:500-1:1000 (ECL) Endogenous Protein. Western Blot: 1:5000 (ECL) Expressed Protein. Positive control: PC3- ARCAP cell lines (human prostate cancer cell Lines) and bovine brain.
Antisera in PBS, pH 7.2, 0.05% sodium azide.
Short term: +4°C; Long term: Add glycerol (40-50%) -20°C.
PAK6 is a member of a family of p21-stimulated serine/threonine protein kinases, which contain an amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. These kinases function in a number of cellular processes, including cytoskeleton rearrangement, apoptosis, and the mitogen-activated protein (MAP) kinase signaling pathway.