PAK3

p21 protein (Cdc42/Rac)-activated kinase 3

Serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell migration, or cell cycle regulation. Plays a role in dendrite spine morphogenesis as well as synapse formation and plasticity. Acts as downstream effector of the small GTPases CDC42 and RAC1. Activation by the binding of active CDC42 and RAC1 results in a conformational change and a subsequent autophosphorylation on several serine and/or threonine residues. Phosphorylates MAPK4 and MAPK6 and activates the downstream target MAPKAPK5, a regulator of F-actin polymerization and cell migration. Additionally, phosphorylates TNNI3/troponin I to modulate calcium sensitivity and relaxation kinetics of thin myofilaments. May also be involved in early neuronal development.

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Products

Antibodies (39)

ELISA Kits (2)

Proteins (2)

Type

Cell-Based (1)

Cell-Based Phosphorylation (1)

Primary (39)

Recombinant (2)

Target

PAK3 (43)

Reactivity

Human (41)

Mouse (27)

Rat (18)

Bat (1)

Chicken (1)

Dog (1)

Guinea pig (1)

Hamster (1)

Horse (1)

Monkey (2)

Pig (1)

Rabbit (1)

Sheep (1)

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Application

IHC (25)

IHC-P (7)

WB (35)

ELISA (25)

IF (3)

Peptide-ELISA (3)

Host

rabbit (34)

mouse (4)

sheep (1)

Product Group

IHCPlus (1)

Isotype

IgG (27)

IgG1 (2)

IgG2a,k (1)

Clonality

monoclonal mc (4)

polyclonal pc (35)

Clone

1H7 (1)

4G8A5 (1)

4G8F11 (1)

Format

96-Well Microplate (2)

APC Conjugated (2)

Azide-free (2)

Biotin Conjugated (3)

FITC Conjugated (3)

HRP Conjugated (3)

PE Conjugated (2)

Unconjugated (26)

Epitope

aa124-152 (7)

aa218-247 (7)

pSer154 (5)

90-170 aa (2)

Asn148 (1)

Internal (1)

N-Terminus (1)

aa121-170 (1)

aa13-49 (1)

aa138-255 (1)

aa99-148 (1)

p154 (1)

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Publications

No (43)

Sample Type

Adherent Cell Cultures (2)

Tag

GST, N-terminus (1)

His,C-terminus (1)

Species

Human (2)

Source

Insect Cells (1)

Wheat Germ Extract (1)

Purification

Purified (1)

Low Endotoxin Level

Low endotoxin level (1)

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PAK3 Antibody (aa124-152) LS-C164516

Antibody:

PAK3 Rabbit anti-Mouse Polyclonal (aa124-152) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

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PAK3 Antibody LS-C499493

Antibody:

PAK3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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PAK3 Antibody (aa218-247) LS-C99501

Antibody:

PAK3 Rabbit anti-Human Polyclonal (aa218-247) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

Select

IHC-plus™ PAK3 Antibody (N-Terminus) LS-B2632

(4.0) Rating

Antibody:

PAK3 Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$460

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PAK3 Antibody (aa124-152) LS-C323763

Antibody:

PAK3 Rabbit anti-Mouse Polyclonal (aa124-152) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

PAK3 Antibody (aa124-152, Biotin) LS-C216593

Antibody:

PAK3 Rabbit anti-Mouse Polyclonal (aa124-152) (Biotin) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

PAK3 Antibody (aa124-152, FITC) LS-C216596

Antibody:

PAK3 Rabbit anti-Mouse Polyclonal (aa124-152) (FITC) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

PAK3 Antibody (aa124-152, Azide-free, HRP) LS-C216597

Antibody:

PAK3 Rabbit anti-Mouse Polyclonal (aa124-152) (Azide-free) (HRP) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

Select

PAK3 Antibody (aa124-152, APC) LS-C216595

Antibody:

PAK3 Rabbit anti-Mouse Polyclonal (aa124-152) (APC) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

PAK3 Antibody (aa124-152, PE) LS-C216600

Antibody:

PAK3 Rabbit anti-Mouse Polyclonal (aa124-152) (PE) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• HRP, Azide-free
• APC
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • HRP, Azide-free
  • APC
  • PE

Select

PAK3 Antibody (phospho-Ser154) LS-C199409

Antibody:

PAK3 Rabbit anti-Human Polyclonal (pSer154) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

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PAK3 Antibody (aa13-49) LS-C408089

Antibody:

PAK3 Rabbit anti-Human Polyclonal (aa13-49) Antibody

Reactivity:

Chicken, Sheep, Rabbit, Mouse, Dog, Guinea pig, Rat, Hamster, Pig, Horse, Bat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

Select

PAK3 Antibody (clone 1H7) LS-C197843

Antibody:

PAK3 Mouse anti-Human Monoclonal (1H7) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

100 µg/$423

Select

PAK3 Antibody (aa218-247) LS-C328135

Antibody:

PAK3 Rabbit anti-Human Polyclonal (aa218-247) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

PAK3 Antibody (aa218-247, Biotin) LS-C220235

Antibody:

PAK3 Rabbit anti-Human Polyclonal (aa218-247) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

PAK3 Antibody (aa218-247, FITC) LS-C220234

Antibody:

PAK3 Rabbit anti-Human Polyclonal (aa218-247) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

PAK3 Antibody (aa218-247, APC) LS-C220233

Antibody:

PAK3 Rabbit anti-Human Polyclonal (aa218-247) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

PAK3 Antibody (aa218-247, PE) LS-C220238

Antibody:

PAK3 Rabbit anti-Human Polyclonal (aa218-247) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

PE Conjugated

Price:

200 µl/$952

Select

PAK3 Antibody (aa218-247, Azide-free, HRP) LS-C220237

Antibody:

PAK3 Rabbit anti-Human Polyclonal (aa218-247) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• PE
• HRP, Azide-free

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • PE
  • HRP, Azide-free

Select

PAK3 Antibody (90-170 aa) LS-C385347

Antibody:

PAK3 Rabbit anti-Human Polyclonal (90-170 aa) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

PAK3 Antibody (90-170 aa) LS-C381387

Antibody:

PAK3 Rabbit anti-Human Polyclonal (90-170 aa) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

PAK3 Antibody (phospho-Ser154) LS-C826463

Antibody:

PAK3 Rabbit anti-Human Polyclonal (pSer154) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$357

Select

PAK3 Antibody (clone 4G8F11) LS-C682432

Antibody:

PAK3 Mouse anti-Human Monoclonal (4G8F11) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µl/$459

Select

PAK3 Antibody (clone 4G8A5) LS-C682435

Antibody:

PAK3 Mouse anti-Human Monoclonal (4G8A5) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µl/$459

Select

PAK3 Antibody (Asn148) LS-C177785

Antibody:

PAK3 Rabbit anti-Human Polyclonal (Asn148) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$321; 100 µl/$403

Viewing 1-25 of 43 product results

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