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Anti-PAK1 Antibody (aa178-227) IHC-plus™ LS-B7619

Note: This antibody replaces LS-C117687
Catalog Size Price
LS-B7619-50 50 µl Unavailable

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Anti-PAK1 Antibody (aa178-227) IHC-plus™ LS-B7619
Rabbit Polyclonal (IgG) to Human PAK1
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IHC - Paraffin, Immunofluorescence, Western blot, ELISA
Unconjugated
Immunohistochemistry Image

100% Guaranteed
Rabbit Polyclonal (IgG) to Human PAK1
Human, Mouse, Rat
IHC - Paraffin, Immunofluorescence, Western blot, ELISA
Unconjugated

Details

Human PAK1
Rabbit
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • IHC - Paraffin (1:100)
  • Immunofluorescence (1:100 - 1:500)
  • Western blot (1:500 - 1:1000)
  • ELISA (1:1000)

Specificity and Use

PAK1 antibody was raised against synthetic peptide from human PAK1 (aa178-227).
aa178-227
PAK1 Antibody detects endogenous levels of total PAK1 protein.

Packaging

PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol
Long term: -20°C; Short term: +4°C; Avoid freeze-thaw cycles.
For research use only.

About PAK1

Q13153 NM_002576 NP_002567.3

PAK1 Antibody, Alpha-PAK Antibody, p21-activated kinase 1 Antibody, p65-PAK Antibody, Rac/p21-activated kinase Antibody, STE20 homolog, yeast Antibody, PAKalpha Antibody, PAK-1 Antibody

Protein kinase involved in intracellular signaling pathways downstream of integrins and receptor-type kinases that plays an important role in cytoskeleton dynamics, in cell adhesion, migration, proliferation, apoptosis, mitosis, and in vesicle-mediated transport processes. Can directly phosphorylate BAD and protects cells against apoptosis. Activated by interaction with CDC42 and RAC1. Functions as GTPase effector that links the Rho-related GTPases CDC42 and RAC1 to the JNK MAP kinase pathway.

Immunohistochemistry

Immunohistochemistry
Anti-PAK1 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7619 dilution 1:100.

Immunofluorescence

Immunofluorescence
Immunofluorescence of HeLa cells, using PAK1 Antibody. The picture on the right is treated with the synthesized peptide.

Western blot

Western blot
Western blot of extracts from 293 cells, treated with Etoposide 25 uM 60', using PAK1 Antibody. The lane on the right is treated with the synthesized peptide.

Requested From: 
Date Requested: 10/17/2017

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