Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
(tested or 100% immunogen sequence identity)
Ammonium sulfate precipitation
IHC - Paraffin (5 µg/ml)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
PACAP antibody was raised against synthetic peptide corresponding to part of the native molecule conjugated to Keyhole limpet Hemocyanin. Proprietary, 14 amino acid peptide sequence of PACAP-38, conjugated with KLH.
Recognizes PACAP-38 and has the following cross reactivates. PACAP Immunogen, 75%; PACAP-27, 22%; PACAP Related Peptide, 9%; VIP, 2%; All tested in simple ELISA assay.
PACAP is a secreted proprotein that is further processed into multiple mature peptides. These peptides stimulate adenylate cyclase and increase cyclic adenosine monophosphate (cAMP) levels, resulting in the transcriptional activation of target genes. The products of this gene are key mediators of neuroendocrine stress responses. Alternative splicing results in multiple transcript variants.