PABPC1 / PABP1

poly(A) binding protein, cytoplasmic 1

Binds the poly(A) tail of mRNA, including that of its own transcript. May be involved in cytoplasmic regulatory processes of mRNA metabolism such as pre-mRNA splicing. Its function in translational initiation regulation can either be enhanced by PAIP1 or repressed by PAIP2. Can probably bind to cytoplasmic RNA sequences other than poly(A) in vivo. Involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain. Involved in regulation of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons; for the recognition of premature termination codons (PTC) and initiation of NMD a competitive interaction between UPF1 and PABPC1 with the ribosome-bound release factors is proposed.

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Products

Antibodies (16)

Proteins (5)

Type

Over-Expression Lysate (2)

Primary (16)

Recombinant (3)

Target

PABPC1 / PABP1 (21)

Reactivity

Human (16)

Mouse (10)

Rat (9)

Bovine (3)

Chicken (5)

Chimpanzee (3)

Dog (3)

Gibbon (3)

Guinea pig (3)

Horse (3)

Monkey (3)

Orangutan (3)

Pig (3)

Rabbit (5)

Sheep (3)

Xenopus (2)

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Application

IHC (4)

IHC-P (3)

WB (16)

Flo (1)

ELISA (6)

ICC (1)

IF (3)

IP (3)

Host

rabbit (14)

mouse (2)

Product Group

IHCPlus (1)

Isotype

IgG (11)

IgG2b (2)

Clonality

monoclonal mc (2)

polyclonal pc (14)

Clone

10E10 (2)

Format

Biotin Conjugated (1)

FITC Conjugated (1)

HRP Conjugated (1)

Preservative Free (1)

Unconjugated (13)

Epitope

aa431-480 (4)

aa394-636 (2)

aa250-279 (1)

Publications

No (21)

Tag

GST (1)

His-SUMO (1)

Myc-DDK (Flag) (3)

Species

Human (4)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (1)

Select

Human PABPC1 / PABP1 Protein (Recombinant His-SUMO) (aa1-370) - LS-G21033

Source:

E. coli

Tag:

His-SUMO

Molecular Weight:

57.8 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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PABPC1 / PABP1 Antibody LS-C753951

Antibody:

PABPC1 / PABP1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IF, IHC, IP, WB

Format:

Unconjugated

Price:

100 µg/$331

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IHC-plus™ PABPC1 / PABP1 Antibody (aa394-636) LS-B8470

(4.0) Rating

Antibody:

PABPC1 / PABP1 Rabbit anti-Human Polyclonal (aa394-636) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µg/$485

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PABPC1 / PABP1 Antibody LS-C778021

Antibody:

PABPC1 / PABP1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$357

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PABPC1 / PABP1 Antibody (aa431-480) LS-C101839

Antibody:

PABPC1 / PABP1 Rabbit anti-Human Polyclonal (aa431-480) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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PABPC1 / PABP1 Antibody (aa431-480, HRP) LS-C440279

Antibody:

PABPC1 / PABP1 Rabbit anti-Human Polyclonal (aa431-480) (HRP) Antibody

Reactivity:

Chicken, Sheep, Bovine, Rabbit, Mouse, Dog, Guinea pig, Pig, Horse, Rat, Chimpanzee, Orangutan, Gibbon, Human, Monkey

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

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PABPC1 / PABP1 Antibody (aa431-480, Biotin) LS-C440277

Antibody:

PABPC1 / PABP1 Rabbit anti-Human Polyclonal (aa431-480) (Biotin) Antibody

Reactivity:

Chicken, Sheep, Bovine, Rabbit, Mouse, Dog, Guinea pig, Pig, Horse, Rat, Chimpanzee, Orangutan, Gibbon, Human, Monkey

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

PABPC1 / PABP1 Antibody (aa431-480, FITC) LS-C440278

Antibody:

PABPC1 / PABP1 Rabbit anti-Human Polyclonal (aa431-480) (FITC) Antibody

Reactivity:

Chicken, Sheep, Bovine, Rabbit, Mouse, Dog, Guinea pig, Pig, Horse, Rat, Chimpanzee, Orangutan, Gibbon, Human, Monkey

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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PABPC1 / PABP1 Antibody (clone 10E10) LS-C82271

Antibody:

PABPC1 / PABP1 Mouse anti-Human Monoclonal (10E10) Antibody

Reactivity:

Xenopus, Chicken, Rabbit, Human

Applications:

ELISA, ICC, IF, IP, WB

Format:

Unconjugated

Price:

0.05 mg/$429

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PABPC1 / PABP1 Antibody (clone 10E10) LS-C82229

Antibody:

PABPC1 / PABP1 Mouse anti-Human Monoclonal (10E10) Antibody

Reactivity:

Xenopus, Chicken, Rabbit, Human

Applications:

ELISA, IF, IP, WB

Format:

Unconjugated

Price:

0.1 mg/$482

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PABPC1 / PABP1 Antibody (aa250-279) LS-C163331

Antibody:

PABPC1 / PABP1 Rabbit anti-Human Polyclonal (aa250-279) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

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PABPC1 / PABP1 Antibody (aa394-636) LS-C144925

Antibody:

PABPC1 / PABP1 Rabbit anti-Human Polyclonal (aa394-636) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

100 µl/$440; 200 µl/$468

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PABPC1 / PABP1 Antibody (Preservative Free) LS-C814969

Antibody:

PABPC1 / PABP1 Rabbit anti-Human Polyclonal (Preservative Free) Antibody

Reactivity:

Human

Applications:

IHC-P, WB

Format:

Unconjugated, Preservative Free

Price:

100 µl/$412

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PABPC1 / PABP1 Antibody LS-C401836

Antibody:

PABPC1 / PABP1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

Select

PABPC1 / PABP1 Antibody LS-C405147

Antibody:

PABPC1 / PABP1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

Select

PABPC1 / PABP1 Antibody LS-C768832

Antibody:

PABPC1 / PABP1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

Select

PABPC1 / PABP1 Antibody LS-C749853

Antibody:

PABPC1 / PABP1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

Select

Human PABPC1 / PABP1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G88681

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

70.5 kDa

Price:

20 µg/$150

Select

Human PABPC1 / PABP1 Protein (Recombinant GST) (Full Length) - LS-G33223

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

97.1 kDa

Price:

2 µg/$439

Select

Human PABPC1 / PABP1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G71073

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

70.5 kDa

Price:

20 µg/$1,107

Select

PABPC1 / PABP1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G117895

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

70.5 kDa

Price:

100 µg/$494

Viewing 1-21 of 21 product results

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