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| Catalog Number | Size | Price |
|---|---|---|
| LS-C10119-50 | 50 µg (0.1 mg/ml) | $578 |
| LS-C10119-100 | 100 µg | $925 |
Monoclonal Mouse anti‑Human p66 / SHC Antibody (N‑Terminus, WB) LS‑C10119
Monoclonal Mouse anti‑Human p66 / SHC Antibody (N‑Terminus, WB) LS‑C10119
Antibody:
p66 / SHC Mouse anti-Human Monoclonal (N-Terminus) Antibody
Application:
WB, ELISA
Reactivity:
Human
Format:
Unconjugated, Unmodified
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Antibody:
p66 / SHC Mouse anti-Human Monoclonal (N-Terminus) Antibody
Application:
WB, ELISA
Reactivity:
Human
Format:
Unconjugated, Unmodified
Specifications
Description
SHC antibody LS-C10119 is an unconjugated mouse monoclonal antibody to human SHC (p66) (N-Terminus). Validated for ELISA and WB. Cited in 2 publications.
Target
Human p66 / SHC
Synonyms
SHC1 | p46 shc | p52 shc | SH2 domain protein C1 | p66 | SHCA | SHC | SHC-transforming protein 1 | SHC-transforming protein 3 | SHC-transforming protein A
Host
Mouse
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
IgG1
Monoclonal
Conjugations
Unconjugated
Purification
Gel filtration
Modifications
Unmodified
Immunogen
Synthetic peptide corresponding to a portion of N-Terminus p66Shc.
Epitope
N-Terminus
Specificity
Recognizes the N-terminus of human p66Shc. Species cross-reactivity: mouse, rat and canine.
Applications
- Western blot (0.5 µg/ml)
- ELISA
Usage
Suitable for use in ELISA and Western Blot. Western Blot: 0.5 ug/ml for HRP/ECL detection. Recommended blocking buffer: Casein/Tween 20 based blocking and blot incubation buffer.
Presentation
PBS, pH 7.4, 0.09% sodium azide, PEG, sucrose, 50% glycerol
Storage
Short term: store at 4°C. Long term: aliquot and store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About p66 / SHC
LSBio Ratings
p66 / SHC Antibody (N-Terminus) for WB/Western, ELISA LS-C10119 has an LSBio Rating of
Publications (4.1)
Learn more about The LSBio Ratings Algorithm
Publications (2)
p66Shc: A novel biomarker of tubular oxidative injury in patients with diabetic nephropathy. Xu X, Zhu X, Ma M, Han Y, Hu C, Yuan S, Yang Y, Xiao L, Liu F, Kanwar YS, Sun L. Scientific reports. 2016 6:29302. (WB; Human)
The redox protein p66(shc) mediates cochlear vascular dysfunction and transient noise-induced hearing loss. A R Fetoni, S L M Eramo, F Paciello, R Rolesi, D Samengo, G Paludetti, D Troiani, G Pani. Scientific reports. 2016 May;6:25450.
Customer Reviews (0)
Featured Products
Species:
Human
Applications:
IHC, IHC - Paraffin, Immunofluorescence, Western blot, ELISA, Proximity Ligation Assay
Species:
Human, Monkey, Mouse, Rat, Bovine, Dog, Horse, Pig
Applications:
Western blot, ELISA
Species:
Human, Mouse, Rat
Applications:
IHC, IHC - Paraffin, Western blot, Flow Cytometry
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/19/2024
Date Requested: 4/19/2024
