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Anti-SQSTM1 Antibody LS-C180078

Catalog	Size	Price
LS-C180078-100	100 µl (0.2 mg/ml)	Unavailable

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105 SQSTM1 Antibodies

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Anti-SQSTM1 Antibody (aa421-440) LS-C37984

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Application:	IHC - Paraffin, IHC - Frozen, ICC, Western blot
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Anti-SQSTM1 Antibody (C-Terminus) IHC-plus™ LS-B4617

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Anti-SQSTM1 Antibody (aa323-372) IHC-plus™ LS-B5839

Antibody:	Rabbit Polyclonal to Human SQSTM1
Reactivity:	Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Horse, Pig, Rabbit, Sheep, Chicken
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Antibody:	Rabbit Polyclonal to Human SQSTM1
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Anti-SQSTM1 Antibody (aa91-110) LS-C313090

Antibody:	Rabbit Polyclonal (IgG) to Human SQSTM1
Reactivity:	Human, Monkey, Horse, Pig, Rabbit
Application:	IHC - Paraffin, ICC, Western blot
Format:	Unconjugated

Antibody:	Rabbit Polyclonal to Human SQSTM1
Reactivity:	Human, Mouse, Rat, Sheep
Application:	ICC, Western blot
Format:	Unconjugated

Details

Target:	Human SQSTM1
Host:	Rabbit
Reactivity:	Human, Mouse, Rat, Sheep (tested or 100% immunogen sequence identity)
Clonality:	Polyclonal
Conjugations:	Unconjugated
Purification:	Immunoaffinity purified
Modifications:	Unmodified

Applications

Approved:

ICC (1:25 - 1:200)
Western blot (1:4000)

Specificity and Use

Immunogen:

SQSTM1 antibody was raised against a genomic peptide made to an internal region of the human p62/SQSTM1 protein (within residues 300-450). [Swiss-Prot Q13501].

Packaging

Presentation:	PBS, 0.1% BSA, 30% glycerol, 0.05% sodium azide.
Storage:	Store at -20°C. Avoid freeze-thaw cycles.
Restrictions:	For research use only.

About SQSTM1

Uniprot: Q13501 NCBI: NM_003900 NP_003891.1

Synonyms: SQSTM1 Antibody, A170 Antibody, ORCA Antibody, OSIL Antibody, Paget disease of bone 3 Antibody, p60 Antibody, p62 Antibody, PDB3 Antibody, Sequestosome-1 Antibody, Ubiquitin-binding protein p62 Antibody, Oxidative stress induced like Antibody, p62B Antibody, ZIP3 Antibody, Sequestosome 1 Antibody, EBI3-associated protein p60 Antibody, EBIAP Antibody

Description: Autophagy receptor that interacts directly with both the cargo to become degraded and an autophagy modifier of the MAP1 LC3 family. Required both for the formation and autophagic degradation of polyubiquitin-containing bodies, called ALIS (aggresome-like induced structures) and links ALIS to the autophagic machinery. Involved in midbody ring degradation. May regulate the activation of NFKB1 by TNF-alpha, nerve growth factor (NGF) and interleukin-1.

(More About SQSTM1)