Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Hamster, Horse, Pig, Rabbit, Chicken
IHC - Paraffin, Western blot
Goat Polyclonal to Human P2RY1 / P2Y1
Human, Monkey, Rat, Bat, Bovine, Guinea pig, Hamster, Horse, Pig, Rabbit, Chicken
Human P2RY1 / P2Y1
Human, Monkey, Rat, Bat, Bovine, Guinea pig, Hamster, Horse, Pig, Rabbit, Chicken (tested or 100% immunogen sequence identity)
Mouse, Dog (at least 90% immunogen sequence identity)
IHC - Paraffin
Specificity and Use
P2RY1 / P2Y1 antibody was raised against synthetic peptide C-KDLDNSPLRRK from an internal region of human P2RY1 / P2Y1 (NP_002554.1). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Rat, Hamster, Bat, Bovine, Horse, Rabbit, Pig, Guinea pig, Turkey, Chicken, Platypus, Lizard (100%); Mouse, Elephant, Panda, Dog, Opossum (91%); Toxoplasma, Neospora (82%).
LS-E26537 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C55222. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
P2RY1 / P2Y1 belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor functions as a receptor for extracellular ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation.