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Anti-P2RX7 / P2X7 Antibody (aa13-26) IHC-plus™ LS-B4401

Note: This antibody replaces LS-C108123

Ordering

Wt. Vol. Conc. Price
50 µg - 0.5 mg/ml $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular P2RX7 / P2X7 Antibodies

Anti-P2RX7 / P2X7 Antibody (Internal) IHC-plus™ LS-A9585
Rabbit Polyclonal to Human P2RX7 / P2X7
Human, Monkey
IHC - Paraffin
Unconjugated
Immunohistochemistry Image
Anti-P2RX7 / P2X7 Antibody (aa13-26) IHC-plus™ LS-B4401
Goat Polyclonal to Human P2RX7 / P2X7
Human, Hamster, Pig
IHC - Paraffin, Western blot, ELISA
Unconjugated
Immunohistochemistry Image
Anti-P2RX7 / P2X7 Antibody (aa47-334, FITC) LS-C424040
Rabbit Polyclonal (IgG) to Human P2RX7 / P2X7
Human
IHC - Paraffin, IHC - Frozen, ICC, Western blot, ELISA
FITC Conjugated

100% Guaranteed 100% Guaranteed
Goat Polyclonal to Human P2RX7 / P2X7
Human, Hamster, Pig
IHC - Paraffin, Western blot, ELISA
Unconjugated

Details

Human P2RX7 / P2X7
Goat
Human, Hamster, Pig (tested or 100% immunogen sequence identity)
Monkey, Mouse, Rat, Guinea pig (at least 90% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • IHC - Paraffin (3.75 µg/ml)
  • Western blot (1 - 3 µg/ml)
  • ELISA (1:16000)

Specificity and Use

P2RX7 / P2X7 antibody was raised against synthetic peptide YETNKVTRIQSMNY-C from the N-terminus of human P2RX7 / P2X7 (NP_002553.2). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Marmoset, Hamster, Pig (100%); Monkey, Mouse, Rat, Guinea pig (93%); Elephant, Panda, Dog, Rabbit (86%).
LS-E27121 - Lyophilized - 100 µg - $145.00
aa13-26
Human P2RX7 / P2X7.
Western Blot: Approx 37kD and 70kD band observed in Human Brain (Frontal Cortex) lysates (calculated MW of 68.6kD according to NP_002553.2). Recommended concentration: 1-3 ug/ml.

Packaging

Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Store at -20°C. Minimize freezing and thawing.
For research use only.

About P2RX7 / P2X7

Q99572 NM_002562 NP_002553.3

P2RX7 Antibody, ATP receptor Antibody, p2X purinoceptor 7 Antibody, p2X receptor 7 Antibody, p2X7 purinoceptor Antibody, p2Z receptor Antibody, Purinergic receptor Antibody, p2RX7 Antibody, p2X7 Antibody, p2X7 receptor Antibody

P2RX7 / P2X7 belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression.

Immunohistochemistry

Immunohistochemistry
Anti-P2RX7 / P2X7 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4401 concentration 3.75 ug/ml.

Immunohistochemistry

Immunohistochemistry
Anti-P2RX7 / P2X7 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4401 concentration 3.75 ug/ml.

Western blot

Western blot
P2RX7 antibody staining (0.3 ug/ml) of Human Brain (Frontal Cortex) lysate (35 ug protein in RIPA buffer) with (B) and without (A) blocking with the immunizing peptide. Primary incubation was 1 hour. Detected by chemiluminescence.
 

Requested From: United States
Date Requested: 12/2/2016

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