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P2RX6 / P2X6
purinergic receptor P2X, ligand-gated ion channel, 6
P2RX6 / P2X6 belongs to the family of P2X receptors, which are ATP-gated ion channels and mediate rapid and selective permeability to cations. This gene is predominantly expressed in skeletal muscle, and regulated by p53. The encoded protein is associated with VE-cadherin at the adherens junctions of human umbilical vein endothelial cells. Alternative splicing results in multiple transcript variants. A related pseudogene, which is also located on chromosome 22, has been identified.
| Gene Name: | purinergic receptor P2X, ligand-gated ion channel, 6 |
| Family/Subfamily: | Ion Channel , P2X receptor |
| Synonyms: | P2RX6, ATP receptor, p2RXL1, p2X purinoceptor 6, p2RX6, p2X6, p2X6 purinoceptor, p2XM, Purinergic receptor, Purinoreceptor P2X6, Skeletal muscle-expressed P2X, p2X receptor 6, p2X-like 1, Purinergic receptor P2X-like 1, Purinoceptor P2X6 |
| Target Sequences: | NM_005446 NP_005437.2 O15547 |
Publications (2)
1
Time-of-day-dependent expression of purinergic receptors in mouse suprachiasmatic nucleus. Lommen J, Stahr A, Ingenwerth M, Ali AAH, von Gall C. Cell and tissue research. 2017 (IHC, WB; Mouse, Human)
[Full Text Article]
[PubMed:28547658]
[PMC:PMC5579179]
Related Antibodies: LS-C94426.
2
Spatiotemporal and anatomical analyses of P2X receptor-mediated neuronal and glial processing of sensory signals in the rat dorsal horn. Aoyama R, Okada Y, Yokota S, Yasui Y, Fukuda K, Shinozaki Y, Yoshida H, Nakamura M, Chiba K, Yasui Y, Kato F, Toyama Y. Pain. 2011 Sep;152:2085-97. [Full Text Article]
[PubMed:21669492]
Related Antibodies: LS-B154.
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P2RX6 / P2X6
(23)
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rabbit
(19)
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(9)
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(19)
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(3)
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(1)
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(8)
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aa198-226
(7)
aa35-84
(4)
aa66-115
(4)
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(1)
aa387-406
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(21)
Yes
(2)
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(4)
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Human
(2)
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293T Cells
(2)
HEK 293 Cells
(2)
P2RX6 / P2X6 Rabbit anti-Human Polyclonal (aa66-115) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
P2RX6 / P2X6 Rabbit anti-Human Polyclonal (aa66-115) (HRP) Antibody
Rabbit, Guinea pig, Bovine, Rat, Pig, Horse, Gibbon, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
P2RX6 / P2X6 Rabbit anti-Human Polyclonal (aa66-115) (Biotin) Antibody
Rabbit, Guinea pig, Bovine, Rat, Pig, Horse, Gibbon, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
P2RX6 / P2X6 Rabbit anti-Human Polyclonal (aa66-115) (FITC) Antibody
Rabbit, Guinea pig, Bovine, Rat, Pig, Horse, Gibbon, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
P2RX6 / P2X6 Rabbit anti-Mouse Polyclonal (Cytoplasmic Domain) Antibody
Mouse, Rat
IHC, WB
Unconjugated
500 µg/$393
P2RX6 / P2X6 Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody
Human
IHC, WB
Unconjugated
500 µg/$393
P2RX6 / P2X6 Rabbit anti-Human Polyclonal (aa198-226) Antibody
Human
WB
Unconjugated
400 µl/$393
P2RX6 / P2X6 Rabbit anti-Human Polyclonal (aa198-226) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
P2RX6 / P2X6 Rabbit anti-Human Polyclonal (aa198-226) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
P2RX6 / P2X6 Rabbit anti-Human Polyclonal (aa198-226) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
P2RX6 / P2X6 Rabbit anti-Human Polyclonal (aa198-226) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
P2RX6 / P2X6 Rabbit anti-Human Polyclonal (aa198-226) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
P2RX6 / P2X6 Rabbit anti-Human Polyclonal (aa198-226) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
P2RX6 / P2X6 Rabbit anti-Human Polyclonal (aa35-84) Antibody
Human
WB
Unconjugated
100 µl/$424
P2RX6 / P2X6 Rabbit anti-Human Polyclonal (aa35-84) (HRP) Antibody
Human, Chimpanzee
WB
HRP Conjugated
100 µl/$469
P2RX6 / P2X6 Rabbit anti-Human Polyclonal (aa35-84) (Biotin) Antibody
Human, Chimpanzee
WB
Biotin Conjugated
100 µl/$469
P2RX6 / P2X6 Rabbit anti-Human Polyclonal (aa35-84) (FITC) Antibody
Human, Chimpanzee
WB
FITC Conjugated
100 µl/$469
P2RX6 / P2X6 Rabbit anti-Human Polyclonal (aa387-406) Antibody
Human
WB
Unconjugated
10 µg/$318; 100 µg/$470
P2RX6 / P2X6 Rabbit anti-Human Polyclonal Antibody
Mouse
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
293T Cells
Myc-DDK (Flag)
45.6 kDa
20 µg/$150
293T Cells
Myc-DDK (Flag)
48.6 kDa
20 µg/$215
HEK 293 Cells
Myc-DDK (Flag)
48.6 kDa
100 µg/$710
HEK 293 Cells
Myc-DDK (Flag)
45.6 kDa
100 µg/$494
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