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Anti-P2RX6 / P2X6 Antibody (aa66-115) IHC-plus™ LS-B154

Note: This antibody replaces LS-C19190

Ordering

Wt. Vol. Conc. Price
50 µg 50 µl 1 mg/ml $450
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular P2RX6 / P2X6 Antibodies

Anti-P2RX6 / P2X6 Antibody (Extracellular Domain) LS-C94362
Rabbit Polyclonal (IgG) to Human P2RX6 / P2X6
Human
Unconjugated
Anti-P2RX6 / P2X6 Antibody (Cytoplasmic Domain) LS-C94426
Rabbit Polyclonal (IgG) to Mouse P2RX6 / P2X6
Mouse, Rat
Unconjugated
Anti-P2RX6 / P2X6 Antibody (aa198-226) LS-C163316
Rabbit Polyclonal to Human P2RX6 / P2X6
Human
Western blot
Unconjugated
Western blot Image

100% Guaranteed 100% Guaranteed Publications Publications (1)
Rabbit Polyclonal to Human P2RX6 / P2X6
Human, Monkey, Rat, Bovine, Guinea pig, Horse, Pig, Rabbit
IHC - Paraffin, Western blot (applications tested for the base form of this product only)
Unconjugated

Details

Human P2RX6 / P2X6
Rabbit
Human, Monkey, Rat, Bovine, Guinea pig, Horse, Pig, Rabbit (tested or 100% immunogen sequence identity)
Mouse, Dog (at least 90% immunogen sequence identity)
Polyclonal
Unconjugated. Also available conjugated with Biotin, FITC, HRP.
Immunoaffinity purified
Unmodified

Applications

  • IHC - Paraffin (1.25 µg/ml)
  • Western blot (0.2 - 1 µg/ml)
  • (applications tested for the base form of this product only)

Specificity and Use

P2RX6 / P2X6 antibody was raised against synthetic peptide located between aa66-115 of human P2RX6 (O15547, NP_005437). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Elephant, Bovine, Rabbit, Horse, Pig, Guinea pig (100%); Mouse, Dog (92%); Rat, Panda, Turkey, Chicken, Platypus (85%); Zebra finch (80%).
LS-E12512 - Lyophilized - 100 µg - $145.00
aa66-115
Human P2RX6 / P2X6
Immunohistochemistry: LS-B154 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B154 was determined to be 1.25 ug/ml.

Packaging

Lyophilized from PBS with 2% sucrose
50 µl After adding water, will consist of PBS buffer with 2% sucrose
Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year); Short term (less than one week): +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

Publications (1)

1
Spatiotemporal and anatomical analyses of P2X receptor-mediated neuronal and glial processing of sensory signals in the rat dorsal horn. Aoyama R, Okada Y, Yokota S, Yasui Y, Fukuda K, Shinozaki Y, Yoshida H, Nakamura M, Chiba K, Yasui Y, Kato F, Toyama Y. Pain. 2011 Sep;152:2085-97. [Full Text Article] [PubMed:21669492]

About P2RX6 / P2X6

O15547 NM_005446 NP_005437.2

P2RX6 Antibody, ATP receptor Antibody, p2RXL1 Antibody, p2X purinoceptor 6 Antibody, p2RX6 Antibody, p2X6 Antibody, p2X6 purinoceptor Antibody, p2XM Antibody, Purinergic receptor Antibody, Purinoreceptor P2X6 Antibody, Skeletal muscle-expressed P2X Antibody, p2X receptor 6 Antibody, p2X-like 1 Antibody, Purinergic receptor P2X-like 1 Antibody, Purinoceptor P2X6 Antibody

P2RX6 / P2X6 belongs to the family of P2X receptors, which are ATP-gated ion channels and mediate rapid and selective permeability to cations. This gene is predominantly expressed in skeletal muscle, and regulated by p53. The encoded protein is associated with VE-cadherin at the adherens junctions of human umbilical vein endothelial cells. Alternative splicing results in multiple transcript variants. A related pseudogene, which is also located on chromosome 22, has been identified.

Immunohistochemistry

Immunohistochemistry
Anti-P2RX6 / P2X6 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B154 concentration 1.25 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Western blot
P2RX6 / P2X6 antibody LS-B154 Western blot of HepG2 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Western blot
HepG2 Cell Lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
 

Requested From: United States
Date Requested: 12/2/2016

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