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Anti-OTUB1 / OTU1 Antibody LS-C211849

Ordering

Wt. Vol. Conc. Price
100 µg - - $315
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular OTUB1 / OTU1 Antibodies

Anti-OTUB1 / OTU1 Antibody (aa1-272, APC) LS-C245209
Mouse Monoclonal (IgG2a) to Human OTUB1 / OTU1
Human
Western blot, ELISA
APC Conjugated
Anti-OTUB1 / OTU1 Antibody (aa1-271, FITC) LS-C304551
Rabbit Polyclonal (IgG) to Rat OTUB1 / OTU1
Rat
Western blot, ELISA
FITC Conjugated
Anti-OTUB1 / OTU1 Antibody (aa1-40) IHC-plus™ LS-B14088
Rabbit Polyclonal (IgG) to Human OTUB1 / OTU1
Human, Monkey, Mouse, Rat, Bovine, Guinea pig, Pig
IHC - Paraffin, Western blot, Immunoprecipitation
Unconjugated
Immunohistochemistry - Paraffin Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal (IgG) to Human OTUB1 / OTU1
Human
IHC, Western blot, ELISA (applications tested for the base form of this product only)
Unconjugated

Details

Human OTUB1 / OTU1
Rabbit
Human (tested or 100% immunogen sequence identity)
IgG Polyclonal
Unconjugated. Also available conjugated with HRP, FITC, Biotin.
Caprylic acid and ammonium sulfate precipitation
Unmodified

Applications

  • IHC
  • Western blot
  • ELISA
  • (applications tested for the base form of this product only)

Specificity and Use

OTUB1 / OTU1 antibody was raised against recombinant human Ubiquitin thioesterase OTUB1 protein.
Human OTUB1 / OTU1

Packaging

PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
For research use only.

About OTUB1 / OTU1

Q96FW1 NM_017670 NP_060140.2

OTUB1 Antibody, Deubiquitinating enzyme OTUB1 Antibody, HSPC263 Antibody, HOTU1 Antibody, OTU-domain Ubal-binding 1 Antibody, OTU1 Antibody, Otubain-1 Antibody, Ubiquitin thioesterase OTUB1 Antibody, OTB1 Antibody

Hydrolase that can specifically remove 'Lys-48'-linked conjugated ubiquitin from proteins and plays an important regulatory role at the level of protein turnover by preventing degradation. Regulator of T-cell anergy, a phenomenon that occurs when T-cells are rendered unresponsive to antigen rechallenge and no longer respond to their cognate antigen. Acts via its interaction with RNF128/GRAIL, a crucial inductor of CD4 T-cell anergy. Isoform 1 destabilizes RNF128, leading to prevent anergy.

Western blot

Western blot
Western blot of Ubiquitin thioesterase OTUB1 antibody at 2 ug/ml. Lane 1: EC109 whole cell lysate. Lane 2: 293T whole cell lysate. Secondary: Goat polyclonal to Rabbit IgG at 1:15000 dilution. Predicted band size: 20 kDa. Observed band size: 80 kDa. This image was taken for the unconjugated form of this product. Other forms have not been tested.
 

Requested From: United States
Date Requested: 12/7/2016

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