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Anti-Osteonectin / SPARC Antibody (clone ON1-1) LS-C83590

Ordering

Wt. Vol. Conc. Price
100 µg 50 µl 2 mg/ml $485
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
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Most Popular Osteonectin / SPARC Antibodies

Anti-Osteonectin / SPARC Antibody (clone 5031) LS-C25800
Mouse Monoclonal [clone 5031] (IgG1) to Human Osteonectin / SPARC
Human, Rat, Bovine
IHC, Western blot, ELISA, Radioimmunoassay
Unconjugated
Anti-Osteonectin / SPARC Antibody (aa1-304, Biotin) LS-C280453
Mouse Monoclonal (IgG1) to Human Osteonectin / SPARC
Human
Western blot
Biotin Conjugated

100% Guaranteed 100% Guaranteed
Mouse Monoclonal [clone ON1-1] (IgG1) to Human Osteonectin / SPARC
Human
IHC - Paraffin, IHC - Frozen, Western blot
Unconjugated

Details

Human Osteonectin / SPARC
Mouse
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [ON1-1]
Unconjugated
Unmodified

Applications

  • IHC - Paraffin (1 - 10 µg/ml)
  • IHC - Frozen (1 - 10 µg/ml)
  • Western blot (1 - 10 µg/ml)

Specificity and Use

Osteonectin / SPARC antibody was raised against bovine bone osteonectin.
Reacts with human and bovine osteonectin as determined by Western Blot, and cross-reacts with rabbit and porcine osteonectin as determined by ELISA. Reacts with both bone and platelet derived osteonectin; it does not react with non-activated platelets, but it does react with thrombin-stimulated platelets, as determined by Flow Cytometry.
Western Blot: Reducing and non-reducing conditions.

Packaging

Lyophilized from 10 mM PBS, pH 7.4 with 1% BSA
50 µl Distilled Water.
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
For research use only.

About Osteonectin / SPARC

P09486 NM_003118 NP_003109.1

SPARC Antibody, Basement-membrane protein 40 Antibody, BM-40 Antibody, Cysteine-rich protein Antibody, ON Antibody, Osteonectin Antibody

SPARC (secreted protein acidic and rich in cysteine)/Osteonectin is a matricellular glycoprotein that modulates cellular interactions with the ECM and is expressed in tissues undergoing remodeling. It functions as a de-adhesive protein, as a modulator of growth factor activity, and as a cell-cycle inhibitor. It induces changes in endothelial cell shape via F-actin, coincident with the appearance of intercellular gaps, that provide a paracellular pathway for extravasation of macromolecules.

Requested From: United States
Date Requested: 12/9/2016

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