Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human (tested or 100% immunogen sequence identity)
Specificity and Use
Osteocalcin antibody was raised against synthetic peptide C-DELADHIGFQEAYRR from an internal region (near C-terminus) of human Osteocalcin (NP_954642.1). Percent identity by BLAST analysis: Hamster, Zebra finch (87%).
LS-E27973 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C186567. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
BGLAP Antibody, Bone Gla protein Antibody, BGP Antibody, OC Antibody, Osteocalcin Antibody
Osteocalcin (BGLAP) is secreted by osteoblasts and plays a role in metabolic regulation. It is pro-osteoblastic (bone-building). It is also implicated in bone mineralization and calcium ion homeostasis. Osteocalcin acts as a hormone in the body, causing beta cells in the pancreas to release more insulin, and at the same time directing fat cells to release the hormone adiponectin, which increases sensitivity to insulin.