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| Catalog Number | Size | Price |
|---|---|---|
| LS-B11477-50 | 50 µl (0.5 mg/ml) | $460 |
1 of 2
2 of 2
Polyclonal Rabbit anti‑Human OSMR / IL‑31R‑Beta Antibody (aa612‑661, IHC, WB) LS‑B11477
Polyclonal Rabbit anti‑Human OSMR / IL‑31R‑Beta Antibody (aa612‑661, IHC, WB) LS‑B11477
Note: This antibody replaces LS-C102225
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Specifications
Description
IL-31R-Beta antibody LS-B11477 is an unconjugated rabbit polyclonal antibody to human IL-31R-Beta (OSMR) (aa612-661). Validated for IHC and WB. Cited in 3 publications.
Target
Human OSMR / IL-31R-Beta
Synonyms
OSMR | IL-31R-beta | IL-31R subunit beta | PLCA1 | Oncostatin M receptor | OSMRB | IL-31 receptor subunit beta | IL-31RB
Host
Rabbit
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
IgG
Polyclonal
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic peptide located between aa612-661 of human OSMR (Q99650, NP_003990). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Marmoset, Dog, Horse, Guinea pig (100%); Elephant (92%); Rabbit (91%); Galago (85%).
Epitope
aa612-661
Specificity
Human OSMR
Applications
- IHC
- IHC - Paraffin (10 µg/ml)
- Western blot (0.2 - 1 µg/ml)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Usage
Western Blot: Suggested dilution at 1µg/ml in 5% skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as second antibody. ELISA titer in peptide based assay: 1:312500.
Presentation
PBS, 0.09% sodium azide, 2% sucrose
Storage
Short term: Store at 2-8°C. Long term: Aliquot and store at -20°C. Avoid freeze/thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About OSMR / IL-31R-Beta
LSBio Ratings
OSMR / IL-31R-Beta Antibody (aa612-661) for IHC, WB/Western LS-B11477 has an LSBio Rating of
Publications (4.2)
Learn more about The LSBio Ratings Algorithm
Publications (3)
Dermal Periostin: A New Player in Itch of Prurigo Nodularis. Takashi Hashimoto, Leigh A Nattkemper, Hei Sung Kim, Christina D Kursewicz, Emilie Fowler, Serena M Shah, Sonali Nanda, Rachel A Fayne, Paolo Romanelli, Gil Yosipovitch. Acta dermato-venereologica. 2020 November;
Mechanisms of Itch in Stasis Dermatitis: Significant Role of IL-31 from Macrophages. Takashi Hashimoto, Christina Dorothy Kursewicz, Rachel Alison Fayne, Sonali Nanda, Serena Maya Shah, Leigh Nattkemper, Hiroo Yokozeki, Gil Yosipovitch. The Journal of investigative dermatology. 2020 Apr;;140:850-859.e3.
Itch intensity in prurigo nodularis is closely related to dermal interleukin-31, oncostatin M, IL-31 receptor alpha and oncostatin M receptor beta. Takashi Hashimoto, Leigh A Nattkemper, Hei Sung Kim, Christina D Kursewicz, Emilie Fowler, Serena M Shah, Sonali Nanda, Rachel A Fayne, John F Paolini, Paolo Romanelli, Gil Yosipovitch. Experimental dermatology. 2021 June;30:804-810.
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Featured Products
Species:
Mouse
Applications:
Flow Cytometry
Species:
Human
Applications:
Flow Cytometry
Species:
Human
Applications:
IHC - Paraffin, Immunoprecipitation, ELISA
Reactivity:
Human
Range:
0.16-10 ng/ml
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/24/2024
Date Requested: 4/24/2024
