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OSM / Oncostatin M

oncostatin M

Growth regulator. Inhibits the proliferation of a number of tumor cell lines. Stimulates proliferation of AIDS-KS cells. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses both type I OSM receptor (heterodimers composed of LIPR and IL6ST) and type II OSM receptor (heterodimers composed of OSMR and IL6ST). Involved in the maturation of fetal hepatocytes, thereby promoting liver development and regeneration.

Gene Name: oncostatin M
Synonyms: OSM, Oncostatin-M, Oncostatin M
Target Sequences: NM_020530 NP_065391.1 P13725

Publications (2)

1
Neutrophil extracellular traps (NETs) contribute to pathological changes of ocular graft-vs.-host disease (oGVHD) dry eye: Implications for novel biomarkers and therapeutic strategies. Seungwon An, Ilangovan Raju, Bayasgalan Surenkhuu, Ji-Eun Kwon, Shilpa Gulati, Muge Karaman, Anubhav Pradeep, Satyabrata Sinha, Christine Mun, Sandeep Jain. The ocular surface. 2019 July;17:589-614. [Full Text Article] [PubMed:30965123] [PMC:PMC6721977] Related Antibodies: LS-C104796.
2
Hyperbaric oxygen suppresses stemness-associated properties and Nanog and oncostatin M expression, but upregulates ß-catenin in orthotopic glioma models. Kun Song, Junrui Chen, Jianbo Ding, Hao Xu, Hongzhi Xu, Zhiyong Qin. The Journal of international medical research. 2019 Mar;48:300060519872898. [Full Text Article] [PubMed:31813325] [PMC:PMC7607208]

☰ Filters
Antibodies (64)
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OSM / Oncostatin M (133)
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OSM / Oncostatin M Antibody - Anti-Human Oncostatin M Western Blot Reduced
Select
OSM / Oncostatin M Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
50 µg/$356; 100 µg/$396
OSM / Oncostatin M Antibody - Western blot - Anti-Oncostatin M Picoband Antibody
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OSM / Oncostatin M Rabbit anti-Mouse Monoclonal Antibody
Mouse, Rat
ELISA, WB
Unconjugated
10 µg/$318; 100 µg/$470
OSM / Oncostatin M Antibody - IHC of paraffin-embedded lung tissue using anti-OSM mouse monoclonal antibody. (Dilution 1:50).
Select
OSM / Oncostatin M Mouse anti-Human Monoclonal (OTI2B6) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
OSM / Oncostatin M ELISA Kit
Select
Sandwich
96-Well Strip Plate
Monkey
15.63 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$863
OSM / Oncostatin M ELISA Kit
Select
Sandwich
96-Well Microplate
Human
1.371 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$588
OSM / Oncostatin M Antibody - OSM / Oncostatin M antibody. IHC(P): Human Intestinal Cancer Tissue.
Select
OSM / Oncostatin M Rabbit anti-Human Polyclonal (aa181-198) Antibody
Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
OSM / Oncostatin M Antibody - Immunohistochemistry of paraffin-embedded human prostate using OSM antibody at dilution of 1:100 (40x lens).
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OSM / Oncostatin M Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
OSM / Oncostatin M Antibody - Western blot of recombinant OSM / Oncostatin M.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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OSM / Oncostatin M Rabbit anti-Mouse Polyclonal (aa25-115) Antibody
Mouse
WB
Unconjugated
100 µl/$301; 200 µl/$340; 500 µl/$470; 1 ml/$535; 2 ml/$698; 5 ml/$1,161
OSM / Oncostatin M ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
Select
E. coli
None
Biologically active
Less than 0.2 EU/µg protein (determined by LAL method).
20.5 kDa (SDS-PAGE)
50 µg/$478; 10 µg/$296; 1 mg/$2,653
OSM / Oncostatin M ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
15.63 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$818
OSM / Oncostatin M Antibody - Anti-OSM / Oncostatin M antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
OSM / Oncostatin M Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
OSM / Oncostatin M Antibody - Anti-OSM / Oncostatin M antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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OSM / Oncostatin M Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA, IHC, IHC-P, WB
HRP Conjugated
50 µg/$294; 100 µg/$360
OSM / Oncostatin M Antibody - Anti-OSM / Oncostatin M antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
OSM / Oncostatin M Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, IHC, IHC-P, WB
Biotin Conjugated
50 µg/$294; 100 µg/$360
OSM / Oncostatin M Antibody - Anti-OSM / Oncostatin M antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
OSM / Oncostatin M Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA, IHC, IHC-P, WB
FITC Conjugated
50 µg/$294; 100 µg/$360
OSM / Oncostatin M Antibody - Oncostatin M antibody IHC-paraffin. IHC(P): Human Intestinal Cancer Tissue.
Select
OSM / Oncostatin M Rabbit anti-Human Polyclonal (aa26-220) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
Select
OSM / Oncostatin M Mouse anti-Human Monoclonal (aa26-221) (1D4B) Antibody
Human
Flo, Neut
Unconjugated
500 µg/$1,079
OSM / Oncostatin M Antibody - Immunohistochemistry of paraffin-embedded Human colon cancer using OSM Polyclonal Antibody at dilution of 1:30.
Select
OSM / Oncostatin M Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
Select
OSM / Oncostatin M Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA
Unconjugated
100 µl/$412
OSM / Oncostatin M Antibody - Western blot analysis of Oncostatin M using anti-Oncostatin M antibody. Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each lane was loaded with 50ug of sample under reducing conditions. Lane 1: rat lung tissue lysates,Lane 2: rat spleen tissue lysates,Lane 3: mouse lung tissue lysates,Lane 4: mouse spleen tissue lysates. After Electrophoresis, proteins were transferred to a Nitrocellulose membrane at 150mA for 50-90 minutes. Blocked the membrane with 5% Non-fat Milk/ TBS for 1.5 hour at RT. The membrane was incubated with rabbit anti-Oncostatin M antigen affinity purified polyclonal antibody at 0.5 µg/mL overnight at 4°C, then washed with TBS-0.1% Tween 3 times with 5 minutes each and probed with a goat anti-rabbit IgG-HRP secondary antibody at a dilution of 1:10000 for 1.5 hour at RT. The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit with Tanon 5200 system. A specific band was detected for Oncostatin M at approximately 28KD. The expected band size for Oncostatin M is at 28KD.
Select
OSM / Oncostatin M Rabbit anti-Rat Polyclonal Antibody
Mouse, Rat
ELISA, WB
Unconjugated
10 µg/$318; 100 µg/$470
OSM / Oncostatin M Antibody - Western blot of recombinant OSM / Oncostatin M.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
OSM / Oncostatin M Rabbit anti-Mouse Polyclonal (aa116-205) Antibody
Mouse
WB
Unconjugated
100 µl/$301; 200 µl/$340; 500 µl/$470; 1 ml/$535; 2 ml/$698; 5 ml/$1,161
Select
HEK 293 Cells
None
Biologically active
Less than 0.2 EU/µg protein (determined by LAL method).
10-40 kDa (SDS-PAGE)
50 µg/$478; 10 µg/$296; 1 mg/$2,653
OSM / Oncostatin M Antibody
Select
OSM / Oncostatin M Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
100 µg/$575
Select
OSM / Oncostatin M Rabbit anti-Human Polyclonal Antibody
Human
ELISA, Func, Neut, WB
Unconjugated
100 µg/$725
OSM / Oncostatin M Antibody - Immunohistochemical analysis of paraffin-embedded human-colon, antibody was diluted at 1:200.
Select
OSM / Oncostatin M Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
Viewing 1-25 of 133 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).