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Anti-OSM / Oncostatin M Antibody LS-C42995


Wt. Vol. Conc. Price
100 µg 100 µl 1 mg/ml $450
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Most Popular OSM / Oncostatin M Antibodies

Anti-OSM / Oncostatin M Antibody LS-C104796
Rabbit Polyclonal to Human OSM / Oncostatin M
IHC, Western blot, ELISA, Neutralization
Immunohistochemistry Image
Anti-OSM / Oncostatin M Antibody (clone 2B6) LS-C114400
Mouse Monoclonal [clone 2B6] (IgG1) to Human OSM / Oncostatin M
IHC - Paraffin, Western blot
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal (IgG) to Human OSM / Oncostatin M
Western blot, ELISA, Functional Assay


Human OSM / Oncostatin M
Human (tested or 100% immunogen sequence identity)
IgG Polyclonal


  • Western blot (0.1 - 0.2 µg/ml)
  • ELISA (0.5 µg/ml)
  • Functional Assay (0.1 - 0.18 µg/ml)

Specificity and Use

OSM / Oncostatin M antibody was raised against recombinant human Oncostatin M.
Recognizes human Oncostatin M (OSM), a 209 amino acid pleiotropic cytokine, originally isolated from PMA (phorbol 12-myristate 13-acetate) treated U937 leukaemia cells and mitogen-activated T lymphocytes. OSM was identified by the ability to inhibit the replication of various human tumor cell lines, but has also been shown to exert a stimulatory effect on fibroblasts, smooth muscle cells and Kaposi's sarcoma cells, and to induce the release of certain cytokines by endothelial cells. OSM signals through binding with low affinity to the gp130 protein present in two cell surface receptors: type I consisting of gp130 and LIFR (leucocyte inhibitory factor receptor) which also acts as a receptor for LIF, and type II consisting of gp130 and OSMR, which mediates OSM specific activities.


Lyophilized, PBS, pH 7.4.
100 µl Distilled Water. For long term storage the addition of 0.09% sodium azide is recommended. For functional studies do not add azide.
For research use only.

About OSM / Oncostatin M

P13725 NM_020530 NP_065391.1

OSM Antibody, Oncostatin-M Antibody, Oncostatin M Antibody

Growth regulator. Inhibits the proliferation of a number of tumor cell lines. Stimulates proliferation of AIDS-KS cells. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses both type I OSM receptor (heterodimers composed of LIPR and IL6ST) and type II OSM receptor (heterodimers composed of OSMR and IL6ST). Involved in the maturation of fetal hepatocytes, thereby promoting liver development and regeneration.

Requested From: United States
Date Requested: 10/28/2016

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