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Anti-OPTN / Optineurin Antibody (aa559-575) IHC-plus™ LS-B3065

Note: This antibody replaces LS-C17028


Wt. Vol. Conc. Price
- 125 µl - $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Most Popular OPTN / Optineurin Antibodies

Anti-OPTN / Optineurin Antibody (aa115-130) IHC-plus™ LS-B2096
Rabbit Polyclonal (IgG) to Human OPTN / Optineurin
Human, Monkey
IHC - Paraffin, Western blot
Immunohistochemistry Image
Anti-OPTN / Optineurin Antibody (aa559-575) IHC-plus™ LS-B3065
Rabbit Polyclonal to Human OPTN / Optineurin
Human, Mouse, Rat
IHC - Paraffin, Western blot
Immunohistochemistry Image
Anti-OPTN / Optineurin Antibody (aa70-96, FITC) LS-C226931
Rabbit Polyclonal (IgG) to Human OPTN / Optineurin
Western blot, ELISA
FITC Conjugated

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Human OPTN / Optineurin
Human, Mouse, Rat
IHC - Paraffin, Western blot


Human OPTN / Optineurin
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Immunoaffinity purified


  • IHC - Paraffin (2.5 µg/ml)
  • Western blot (1:200)

Specificity and Use

OPTN / Optineurin antibody was raised against synthetic peptide corresponding to aa 559-575 (GEVLPDIDTLQIHVMDC) of human, mouse and rat optineurin
Recognizes human, mouse and rat optineurin.
Immunohistochemistry: LS-B3065 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B3065 was determined to be 2.5 ug/ml. Western Blot: 1:200. Incubation time of 1 hour at RT. Overnight incubations at 4uC at lower concentrations can produce optimal results.


TBS, pH 7.4, 0.5 mg/ml BSA, 0.02% sodium azide, 50% glycerol.
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About OPTN / Optineurin

Q96CV9 NM_021980 NP_068815.2

OPTN Antibody, ALS12 Antibody, E3-14.7K-interacting protein Antibody, FIP-2 Antibody, HIP-7 Antibody, HYPL Antibody, Huntingtin yeast partner L Antibody, HIP7 Antibody, TFIIIA-INTP Antibody, NEMO-related protein Antibody, NRP Antibody, Optineurin Antibody, FIP2 Antibody, GLC1E Antibody

Plays an important role in the maintenance of the Golgi complex, in membrane trafficking, in exocytosis, through its interaction with myosin VI and Rab8. Links myosin VI to the Golgi complex and plays an important role in Golgi ribbon formation. Negatively regulates the induction of IFNB in response to RNA virus infection. Plays a neuroprotective role in the eye and optic nerve. Probably part of the TNF-alpha signaling pathway that can shift the equilibrium toward induction of cell death.


Anti-Optineurin antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3065 concentration 5 ug/ml.

Requested From: United States
Date Requested: 10/21/2016

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