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OPRS1 / SIGMAR1

sigma non-opioid intracellular receptor 1

Functions in lipid transport from the endoplasmic reticulum and is involved in a wide array of cellular functions probably through regulation of the biogenesis of lipid microdomains at the plasma membrane. Involved in the regulation of different receptors it plays a role in BDNF signaling and EGF signaling. Also regulates ion channels like the potassium channel and could modulate neurotransmitter release. Plays a role in calcium signaling through modulation together with ANK2 of the ITP3R-dependent calcium efflux at the endoplasmic reticulum. Plays a role in several other cell functions including proliferation, survival and death. Originally identified for its ability to bind various psychoactive drugs it is involved in learning processes, memory and mood alteration.

Gene Name: sigma non-opioid intracellular receptor 1
Synonyms: SIGMAR1, HSigmaR1, ALS16, SIG-1R, Sigma 1-type opioid receptor, SR-BP, Opioid receptor, sigma 1, OPRS1, Sigma1-receptor, SR31747-binding protein, SRBP, Sigma1R, SR-BP1, SR31747 binding protein 1
Target Sequences: NM_005866 NP_005857.1 Q99720

☰ Filters
Antibodies (16)
Proteins (6)
ELISA Kits (5)
Competitive EIA (1)
Custom (4)
Over-Expression Lysate (4)
Primary (16)
Recombinant (2)
OPRS1 / SIGMAR1 (27)
Human (17)
Mouse (8)
Rat (9)
Bovine (1)
Chicken (1)
IHC (9)
IHC-P (2)
WB (12)
Flo (1)
ELISA (5)
Peptide-ELISA (1)
rabbit (16)
Product Group
IHCPlus (1)
IgG (11)
polyclonal pc (16)
96-Well Strip Plate (5)
Biotin Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
Unconjugated (13)
Internal (1)
aa118-147 (1)
aa47-81 (1)
No (27)
Plasma (1)
Serum (1)
GST (1)
Myc-DDK (Flag) (5)
Human (4)
293T Cells (2)
HEK 293 Cells (3)
Wheat Germ Extract (1)
Purified (1)
OPRS1 / SIGMAR1 ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Human
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
OPRS1 / SIGMAR1 Antibody - Western blot of OPRS1 (arrow) using rabbit polyclonal OPRS1 Antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the OPRS1 gene (Lane 2) (Origene Technologies).
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OPRS1 / SIGMAR1 Rabbit anti-Human Polyclonal (aa47-81) Antibody
Human
Flo, WB
Unconjugated
400 µl/$393
OPRS1 / SIGMAR1 Antibody - Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE), at a dilution of 1:100.
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OPRS1 / SIGMAR1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
OPRS1 / SIGMAR1 Antibody - Immunohistochemistry of paraffin-embedded Human gastric cancer using SIGMAR1 Polyclonal Antibody at dilution of 1:50.
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OPRS1 / SIGMAR1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
OPRS1 / SIGMAR1 Antibody - Immunohistochemistry of paraffin-embedded Human gastric cancer using SIGMAR1 Polyclonal Antibody at dilution of 1:50.
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OPRS1 / SIGMAR1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
OPRS1 / SIGMAR1 Antibody - 1:100 staining mouse liver tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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OPRS1 / SIGMAR1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Select
OPRS1 / SIGMAR1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$341
OPRS1 / SIGMAR1 Antibody - Immunohistochemistry of paraffin-embedded Human stomach using SIGMAR1 Polyclonal Antibody.
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OPRS1 / SIGMAR1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
OPRS1 / SIGMAR1 Antibody - Immunohistochemistry image of paraffin-embedded human colon cancer at a dilution of 1:100
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OPRS1 / SIGMAR1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
Select
OPRS1 / SIGMAR1 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
HRP Conjugated
50 µg/$294; 100 µg/$360
Select
OPRS1 / SIGMAR1 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
Biotin Conjugated
50 µg/$294; 100 µg/$360
Select
OPRS1 / SIGMAR1 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
FITC Conjugated
50 µg/$294; 100 µg/$360
Select
OPRS1 / SIGMAR1 Rabbit anti-Human Polyclonal (Internal) Antibody
Human
IHC, WB
Unconjugated
100 µl/$440; 200 µl/$468
Select
OPRS1 / SIGMAR1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
50 µl/$356; 100 µl/$461
Select
OPRS1 / SIGMAR1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
Select
OPRS1 / SIGMAR1 Rabbit anti-Human Polyclonal Antibody
Rat, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
OPRS1 / SIGMAR1 Antibody - Western blot of OPRS1 (arrow) using rabbit polyclonal OPRS1 Antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the OPRS1 gene (Lane 2) (Origene Technologies).
Select
OPRS1 / SIGMAR1 Rabbit anti-Human Polyclonal (aa118-147) Antibody
Human
WB
Unconjugated
400 µl/$393
OPRS1 / SIGMAR1 ELISA Kit
Select
Custom
96-Well Strip Plate
Chicken
1 Plate/$929
OPRS1 / SIGMAR1 ELISA Kit
Select
Custom
96-Well Strip Plate
Mouse
1 Plate/$783
OPRS1 / SIGMAR1 ELISA Kit
Select
Custom
96-Well Strip Plate
Bovine
1 Plate/$783
OPRS1 / SIGMAR1 ELISA Kit
Select
Custom
96-Well Strip Plate
Rat
1 Plate/$783
OPRS1 / SIGMAR1 Protein - Purified recombinant protein SIGMAR1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
24.9 kDa
20 µg/$1,107
Select
293T Cells
Myc-DDK (Flag)
24.9 kDa
20 µg/$150
OPRS1 / SIGMAR1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
21.3 kDa
20 µg/$150
OPRS1 / SIGMAR1 Protein - 12.5% SDS-PAGE of human OPRS1 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
51.5 kDa
2 µg/$439
Viewing 1-25 of 27 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).