Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Rabbit Polyclonal (IgG) to Rat OPRD1 / Delta Opioid Receptor
Rat, Mouse, Rabbit
IHC, ICC, Immunofluorescence
Rat OPRD1 / Delta Opioid Receptor
Rat, Mouse, Rabbit (tested or 100% immunogen sequence identity)
Specificity and Use
Synthetic peptide corresponding to residues 358-372 of rat delta opioid.
Recognizes rat Opioid Receptor, delta. Species cross-reactivity: mouse.
Suitable for use Immunocytochemistry. Not suitable for use in Immunohistochemistry. Immunocytochemistry: 1:500. Transfected cells were processed for indirect immunofluorescence. Media was removed and cells were gently washed 3 times with serum-free media. Following fixation procedure, cells were processed for indirect immunofluorescence.
Coexpression of delta- and mu-opioid receptors in nociceptive sensory neurons. Wang HB, Zhao B, Zhong YQ, Li KC, Li ZY, Wang Q, Lu YJ, Zhang ZN, He SQ, Zheng HC, Wu SX, Hökfelt TG, Bao L, Zhang X. Proceedings of the National Academy of Sciences of the United States of America. 2010 107:13117-22. (ICC; Rat)[Full Text Article]
G-protein coupled receptor that functions as receptor for endogenous enkephalins and for a subset of other opioids. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance.