Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Rabbit Polyclonal to Mouse OPRD1 / Delta Opioid Receptor
Mouse, Human, Rat
IHC - Paraffin, Western blot, Flow Cytometry
Mouse OPRD1 / Delta Opioid Receptor
Mouse, Human, Rat (tested or 100% immunogen sequence identity)
IHC - Paraffin (1:1000)
Western blot (1:1000)
Specificity and Use
OPRD1 / Delta Opioid Receptor antibody was raised against delta opioid receptor N-terminal peptide (LVPSARAELQSSPLV) Percent identity by BLAST analysis: Mouse (100%).
Recognizes Delta opioid receptor.
Immunohistochemistry on CNS tissues fixed in PLP: 1:1000. Reactive on paraffin embedded tissue. Western Blot: 1:1000. Under reducing conditions the antibody will detect major bands at 36 and 72 kD. FACS on human T-cells (Sharp, 2001).
Antiserum. No preservative
Store at -20°C. Aliquot to avoid freeze/thaw cycles. Store undiluted.
G-protein coupled receptor that functions as receptor for endogenous enkephalins and for a subset of other opioids. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance.