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Antibodies > OPG / Osteoprotegerin
OPG / Osteoprotegerin Antibody (clone R110) LS‑C179554
Osteoprotegerin antibody LS-C179554 is an unconjugated mouse monoclonal antibody to human Osteoprotegerin (OPG). Validated for WB.
Catalog
Size
Price
LS-C179554-100
100 µg (1 mg/ml)
Unavailable
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HepG2 Cell Lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Species: Human
Applications: IHC, IHC - Paraffin, IHC - Frozen, ICC, Immunofluorescence, Western blot, Immunoprecipitation, Flow Cytometry

Product Description

Osteoprotegerin antibody LS-C179554 is an unconjugated mouse monoclonal antibody to human Osteoprotegerin (OPG). Validated for WB.
About OPG / Osteoprotegerin
Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. Inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local ratio between TNFSF11 and TNFRSF11B. May also play a role in preventing arterial calcification. May act as decoy receptor for TNFSF10/TRAIL and protect against apoptosis. TNFSF10/TRAIL binding blocks the inhibition of osteoclastogenesis. O00300 NM_002546 NP_002537.3

TNFRSF11B Antibody, OCIF Antibody, OPG Antibody, Osteoprotegerin Antibody, TR1 Antibody
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Specifications

Target
Human OPG / Osteoprotegerin
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG1,k Monoclonal [R110]
Conjugations
Unconjugated
Purification
Protein A purified
Modifications
Unmodified
Applications
  • Western blot (5 µg/ml)
Immunogen
OPG.
Specificity
Human Osteoprotegerin / OPG
Presentation
PBS, pH 7.2, 50% glycerol
Storage
Store at -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.
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Images

Flow Cytometry

Flow Cytometry

Flow Cytometry

Flow Cytometry

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Requested From: 
Date Requested: 6/18/2018
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