Human OPG / Osteoprotegerin

Mouse

Human (tested or 100% immunogen sequence identity)

Monkey (at least 90% immunogen sequence identity)

IgG Monoclonal

98A1071

Unconjugated

Protein G purified

Unmodified

A peptide corresponding to the amino acids 20-37 TQETFPPKYLHYDEETSH of human OPG. The specificity was tested on recombinant OPG by western blot analysis. Percent identity by BLAST analysis: Human, Gibbon (100%); Monkey (94%); Marmoset, Panda, Dog, Horse, Pig, Opossum (89%); Mouse, Rat, Elephant, Bovine (83%).

aa20-37

The Osteoprotegerin antibody, clone 98A1071, detects all forms of Osteoprotegerin including monomeric, dimeric and Osteoprotegerin bound to RANKL (Vandooren, 2008) as well as Osteoprotegerin bound to TRAIL (Sandra, 2006).

• IHC
• IHC - Paraffin (5 µg/ml)
• Western blot

Immunohistochemistry: LS-B2078 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B2078 was determined to be 5 ug/ml.

PBS, 0.05% Sodium Azide

Short term: store at 4°C. Long term: store at -20°C. Avoid freeze-thaw cycles.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: O00300 NCBI: NM_002546 NP_002537.3