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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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OMA1 Antibody (aa359‑408) LS‑C116519 Best Seller
OMA1 antibody LS-C116519 is an unconjugated rabbit polyclonal antibody to OMA1 from human, mouse, rat and other species. Validated for WB.
Catalog
Size
Price
LS-C116519-50
50 µg
Unavailable

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Product Description

OMA1 antibody LS-C116519 is an unconjugated rabbit polyclonal antibody to OMA1 from human, mouse, rat and other species. Validated for WB.
About OMA1
Metalloprotease that is part of the quality control system in the inner membrane of mitochondria. Following stress conditions that induce loss of mitochondrial membrane potential, mediates cleavage of OPA1 at S1 position, leading to OPA1 inactivation and negative regulation of mitochondrial fusion. Its role in mitochondrial quality control is essential for regulating lipid metabolism as well as to maintain body temperature and energy expenditure under cold-stress conditions. Q96E52 AA465440 NP_660286.1

OMA1 Antibody, MPRP-1 Antibody, MPRP1 Antibody, YKR087C Antibody, ZMPOMA1 Antibody


Specifications

Target
Human OMA1
Host
Rabbit
Reactivity
Human, Monkey, Mouse, Rat, Bovine, Dog, Guinea pig, Horse, Pig, Rabbit (tested or 100% immunogen sequence identity)
Predicted
Bat (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with Biotin, FITC, HRP.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot (0.2 - 1 µg/ml)
  • (applications tested for the base form of this product only)
Immunogen
OMA1 antibody was raised against synthetic peptide located between aa359-408 of human OMA1 (Q96E52, NP_660286). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Marmoset (100%); Elephant, Bat, Lizard (92%); Opossum (91%); Mouse, Rat, Panda, Dog, Rabbit, Horse, Pig, Turkey, Zebra finch (85%); Galago, Bovine (84%).
Blocking Peptide
LS-E19033 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C116519. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
aa359-408
Specificity
Human OMA1
Usage
Western Blot: Suggested dilution at 1 ug/ml in 5% skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.
Presentation
Lyophilized from PBS with 2% sucrose
Reconstitution
Distilled water
Storage
Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year); Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Western blot

OMA1 antibody LS-C116519 Western blot of 721_B cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
OMA1 antibody LS-C116519 Western blot of 721_B cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

OMA1 antibody LS-C116519 Western blot of 721_B cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
OMA1 antibody LS-C116519 Western blot of 721_B cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

OMA1 antibody LS-C116519 Western blot of 721_B cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
OMA1 antibody LS-C116519 Western blot of 721_B cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

OMA1 antibody LS-C116519 Western blot of 721_B cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
OMA1 antibody LS-C116519 Western blot of 721_B cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.


Requested From: 
Date Requested: 6/17/2018

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