OAS3 / p100

2'-5'-oligoadenylate synthetase 3, 100kDa

Interferon-induced, dsRNA-activated antiviral enzyme which plays a critical role in cellular innate antiviral response. In addition, it may also play a role in other cellular processes such as apoptosis, cell growth, differentiation and gene regulation. Synthesizes preferentially dimers of 2'-5'-oligoadenylates (2-5A) from ATP which then bind to the inactive monomeric form of ribonuclease L (RNase L) leading to its dimerization and subsequent activation. Activation of RNase L leads to degradation of cellular as well as viral RNA, resulting in the inhibition of protein synthesis, thus terminating viral replication. Can mediate the antiviral effect via the classical RNase L-dependent pathway or an alternative antiviral pathway independent of RNase L. Displays antiviral activity against Chikungunya virus (CHIKV), Dengue virus, Sindbis virus (SINV) and Semliki forest virus (SFV).

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Products

Antibodies (15)

ELISA Kits (5)

Proteins (2)

Type

Custom (1)

Over-Expression Lysate (2)

Primary (15)

Sandwich (4)

Target

OAS3 / p100 (22)

Reactivity

Human (18)

Mouse (1)

Rat (1)

Application

IHC (2)

WB (11)

ELISA (11)

IF (2)

Peptide-ELISA (1)

Host

rabbit (14)

goat (1)

Isotype

IgG (13)

Clonality

polyclonal pc (15)

Format

96-Well Strip Plate (5)

APC Conjugated (1)

Azide-free (1)

Biotin Conjugated (2)

FITC Conjugated (2)

HRP Conjugated (2)

PE Conjugated (1)

Unconjugated (7)

Epitope

aa1056-1087 (7)

Internal Region (1)

Publications

No (22)

Sample Type

Plasma (4)

Serum (4)

Tissue Homogenates (2)

Tag

Myc-DDK (Flag) (2)

Species

Human (1)

Source

293T Cells (1)

HEK 293 Cells (1)

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Human OAS3 / p100 (Sandwich ELISA) ELISA Kit - LS-F8121

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$834

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Human OAS3 / p100 (Sandwich ELISA) ELISA Kit - LS-F12206

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.78 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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Human OAS3 / p100 (Sandwich ELISA) ELISA Kit - LS-F34102

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.781 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$768

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OAS3 / p100 Antibody LS-C667336

Antibody:

OAS3 / p100 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

100 µg/$331

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OAS3 / p100 Antibody LS-C502274

Antibody:

OAS3 / p100 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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OAS3 / p100 Antibody (HRP) LS-C502276

Antibody:

OAS3 / p100 Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

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OAS3 / p100 Antibody (Biotin) LS-C502275

Antibody:

OAS3 / p100 Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

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OAS3 / p100 Antibody (FITC) LS-C502273

Antibody:

OAS3 / p100 Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

Mouse OAS3 / p100 (Sandwich ELISA) ELISA Kit - LS-F18344

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

Select

OAS3 / p100 Antibody (aa1056-1087) LS-C330561

Antibody:

OAS3 / p100 Rabbit anti-Human Polyclonal (aa1056-1087) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

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OAS3 / p100 Antibody (aa1056-1087, Biotin) LS-C245190

Antibody:

OAS3 / p100 Rabbit anti-Human Polyclonal (aa1056-1087) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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OAS3 / p100 Antibody (aa1056-1087, FITC) LS-C245191

Antibody:

OAS3 / p100 Rabbit anti-Human Polyclonal (aa1056-1087) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

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OAS3 / p100 Antibody (aa1056-1087, Azide-free, HRP) LS-C247733

Antibody:

OAS3 / p100 Rabbit anti-Human Polyclonal (aa1056-1087) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

Select

OAS3 / p100 Antibody (aa1056-1087, APC) LS-C245189

Antibody:

OAS3 / p100 Rabbit anti-Human Polyclonal (aa1056-1087) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

OAS3 / p100 Antibody (aa1056-1087, PE) LS-C245193

Antibody:

OAS3 / p100 Rabbit anti-Human Polyclonal (aa1056-1087) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• HRP, Azide-free
• APC
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • HRP, Azide-free
  • APC
  • PE

Select

OAS3 / p100 Antibody (Internal Region) LS-C305838

Antibody:

OAS3 / p100 Goat anti-Human Polyclonal (Internal Region) Antibody

Reactivity:

Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µg/$503

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OAS3 / p100 Antibody LS-C768697

Antibody:

OAS3 / p100 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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OAS3 / p100 Antibody LS-C411016

Antibody:

OAS3 / p100 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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OAS3 / p100 Antibody (aa1056-1087) LS-C100475

Antibody:

OAS3 / p100 Rabbit anti-Human Polyclonal (aa1056-1087) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

400 µl/$393

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Human OAS3 / p100 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G89481

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

121 kDa

Price:

20 µg/$215

Select

Rat OAS3 / p100 (Custom ELISA) ELISA Kit - LS-F18345

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Rat

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

Select

OAS3 / p100 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G115470

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

121 kDa

Price:

100 µg/$710

Viewing 1-22 of 22 product results

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