OAS2

2'-5'-oligoadenylate synthetase 2, 69/71kDa

Interferon-induced, dsRNA-activated antiviral enzyme which plays a critical role in cellular innate antiviral response. In addition, it may also play a role in other cellular processes such as apoptosis, cell growth, differentiation and gene regulation. Synthesizes higher oligomers of 2'-5'-oligoadenylates (2-5A) from ATP which then bind to the inactive monomeric form of ribonuclease L (RNase L) leading to its dimerization and subsequent activation. Activation of RNase L leads to degradation of cellular as well as viral RNA, resulting in the inhibition of protein synthesis, thus terminating viral replication. Can mediate the antiviral effect via the classical RNase L-dependent pathway or an alternative antiviral pathway independent of RNase L.

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Products

Antibodies (49)

Proteins (6)

ELISA Kits (3)

Type

Competitive EIA (1)

Custom (1)

Over-Expression Lysate (4)

Primary (49)

Recombinant (2)

Sandwich (1)

Target

OAS2 (58)

Reactivity

Human (52)

Mouse (1)

Rat (3)

Chimpanzee (6)

Dog (3)

Gibbon (6)

Horse (3)

Monkey (3)

Orangutan (6)

Pig (6)

Rabbit (3)

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Application

IHC (11)

IHC-P (2)

WB (42)

ELISA (9)

ICC (1)

IF (2)

IP (1)

Peptide-ELISA (3)

Host

rabbit (27)

mouse (20)

goat (2)

Product Group

IHCPlus (1)

Isotype

IgG (15)

IgG1 (10)

IgG2a (8)

IgG2b (2)

Clonality

monoclonal mc (20)

polyclonal pc (29)

Clone

OTI2A1 (2)

OTI2G3 (2)

OTI3A3 (2)

OTI3C1 (2)

OTI3D4 (2)

OTI4B11 (2)

OTI5C10 (2)

OTI5C3 (2)

OTI5E1 (2)

OTI6E6 (2)

Format

96-Well Strip Plate (3)

APC (1)

APC Conjugated (2)

Azide-free (1)

Biotin Conjugated (4)

Carrier-free (10)

Cy3 Conjugated (1)

Cy7 Conjugated (1)

FITC Conjugated (4)

HRP Conjugated (4)

PE Conjugated (2)

Unconjugated (31)

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Epitope

aa60-335 (20)

aa11-346 (8)

C-Terminus (6)

aa35-84 (4)

aa398-447 (4)

Internal Region (1)

Internal region (near N-Terminus) (1)

Publications

No (58)

Sample Type

Plasma (2)

Serum (2)

Tissue Homogenates (2)

Tag

GST (1)

His (1)

Myc-DDK (Flag) (4)

Species

Human (4)

Source

293T Cells (2)

E. coli (1)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (1)

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IHC-plus™ OAS2 Antibody (Internal Region) LS-B11266

(4.0) Rating

Antibody:

OAS2 Goat anti-Human Polyclonal (Internal Region) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µg/$485

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Human OAS2 (Sandwich ELISA) ELISA Kit - LS-F8120

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.78 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$834

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OAS2 Antibody LS-C803089

Antibody:

OAS2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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OAS2 Antibody (aa398-447) LS-C80378

Antibody:

OAS2 Rabbit anti-Human Polyclonal (aa398-447) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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OAS2 Antibody LS-C667334

Antibody:

OAS2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, IP, WB

Format:

Unconjugated

Price:

100 µg/$331

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OAS2 Antibody (aa60-335, clone OTI5E1) LS-C336695

Antibody:

OAS2 Mouse anti-Human Monoclonal (aa60-335) (OTI5E1) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$434

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OAS2 Antibody (aa60-335, clone OTI5E1, Carrier-free) LS-C789657

Antibody:

OAS2 Mouse anti-Human Monoclonal (aa60-335) (Carrier-free) (OTI5E1) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

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OAS2 Antibody LS-C816858

Antibody:

OAS2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ICC, IF

Format:

Unconjugated

Price:

100 µl/$412

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OAS2 Antibody (C-Terminus) LS-C328084

Antibody:

OAS2 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

200 µl/$734

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OAS2 Antibody (C-Terminus, Biotin) LS-C280355

Antibody:

OAS2 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

Biotin Conjugated

Price:

200 µl/$952

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OAS2 Antibody (C-Terminus, FITC) LS-C280356

Antibody:

OAS2 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

FITC Conjugated

Price:

200 µl/$952

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OAS2 Antibody (C-Terminus, APC) LS-C280353

Antibody:

OAS2 Rabbit anti-Human Polyclonal (C-Terminus) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

APC Conjugated

Price:

200 µl/$952

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OAS2 Antibody (C-Terminus, PE) LS-C280358

Antibody:

OAS2 Rabbit anti-Human Polyclonal (C-Terminus) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

PE Conjugated

Price:

200 µl/$952

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OAS2 Antibody (C-Terminus, Azide-free, HRP) LS-C280357

Antibody:

OAS2 Rabbit anti-Human Polyclonal (C-Terminus) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• PE
• HRP, Azide-free

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • PE
  • HRP, Azide-free

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OAS2 Antibody LS-C667335

Antibody:

OAS2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$331

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OAS2 Antibody LS-C743332

Antibody:

OAS2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

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OAS2 Antibody (Internal region (near N-Terminus)) LS-C305836

Antibody:

OAS2 Goat anti-Human Polyclonal (Internal region (near N-Terminus)) Antibody

Reactivity:

Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µg/$503

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OAS2 Antibody (aa60-335, clone OTI2A1) LS-C336669

Antibody:

OAS2 Mouse anti-Human Monoclonal (aa60-335) (OTI2A1) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$434

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OAS2 Antibody (aa60-335, clone OTI4B11) LS-C336668

Antibody:

OAS2 Mouse anti-Human Monoclonal (aa60-335) (OTI4B11) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$434

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OAS2 Antibody (aa60-335, clone OTI3C1) LS-C336670

Antibody:

OAS2 Mouse anti-Human Monoclonal (aa60-335) (OTI3C1) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$434

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OAS2 Antibody (aa60-335, clone OTI6E6) LS-C336671

Antibody:

OAS2 Mouse anti-Human Monoclonal (aa60-335) (OTI6E6) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$434

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OAS2 Antibody (aa60-335, clone OTI6E6, Carrier-free) LS-C789626

Antibody:

OAS2 Mouse anti-Human Monoclonal (aa60-335) (Carrier-free) (OTI6E6) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

OAS2 Antibody (aa60-335, clone OTI3A3) LS-C336677

Antibody:

OAS2 Mouse anti-Human Monoclonal (aa60-335) (OTI3A3) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$434

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OAS2 Antibody (aa60-335, clone OTI5C10) LS-C336685

Antibody:

OAS2 Mouse anti-Human Monoclonal (aa60-335) (OTI5C10) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$434

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OAS2 Antibody (aa60-335, clone OTI5C3) LS-C336686

Antibody:

OAS2 Mouse anti-Human Monoclonal (aa60-335) (OTI5C3) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$434

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