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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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OAS1 Antibody (aa370‑382) LS‑C205044
OAS1 antibody LS-C205044 is an unconjugated goat polyclonal antibody to human OAS1. Validated for Peptide-ELISA and WB.
Catalog
Size
Price
LS-C205044-100
100 µg (0.5 mg/ml)
Unavailable

Popular OAS1 Products

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Anti-OAS1 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6622 concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Immunohistochemistry - Paraffin Image
Species: Human
Applications: IHC, ICC, Immunofluorescence, Western blot

Product Description

OAS1 antibody LS-C205044 is an unconjugated goat polyclonal antibody to human OAS1. Validated for Peptide-ELISA and WB.
About OAS1
Interferon-induced, dsRNA-activated antiviral enzyme which plays a critical role in cellular innate antiviral response. In addition, it may also play a role in other cellular processes such as apoptosis, cell growth, differentiation and gene regulation. Synthesizes higher oligomers of 2'-5'-oligoadenylates (2-5A) from ATP which then bind to the inactive monomeric form of ribonuclease L (RNase L) leading to its dimerization and subsequent activation. P00973 NM_016816 NP_058132.2

OAS1 Antibody, 2,5-oligo A synthetase 1 Antibody, 2-5A synthetase 1 Antibody, 2-5A synthase 1 Antibody, 2-5-oligoadenylate synthase 1 Antibody, E18/E16 Antibody, OIASI Antibody, OIAS Antibody, p46/p42 OAS Antibody, IFI-4 Antibody


Specifications

Target
Human OAS1
Host
Goat
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot (1 - 3 µg/ml)
  • Peptide Enzyme-Linked Immunosorbent Assay (1:128000)
Immunogen
OAS1 antibody was raised against synthetic peptide C-THEYPHFSHRPST from an internal region (near C-terminus) of human OAS1 (NP_058132.2). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla (100%).
Epitope
aa370-382
Specificity
Human OAS1. This antibody is expected to recognize isoforms 1 (NP_058132.2) only.
Usage
Peptide ELISA: antibody detection limit dilution 1:128000. Western blot: Approx 50kD band observed in lysates of cell line HepG2 (calculated MW of 46.0kD according to NP_058132.2). Recommended concentration: 1-3 ug/ml.
Presentation
Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Storage
Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Western blot

OAS1 antibody (1 ug/ml) staining of HepG2 lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
OAS1 antibody (1 ug/ml) staining of HepG2 lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Western blot

OAS1 antibody (1 ug/ml) staining of HepG2 lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
OAS1 antibody (1 ug/ml) staining of HepG2 lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Western blot

OAS1 antibody (1 ug/ml) staining of HepG2 lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
OAS1 antibody (1 ug/ml) staining of HepG2 lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Western blot

OAS1 antibody (1 ug/ml) staining of HepG2 lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
OAS1 antibody (1 ug/ml) staining of HepG2 lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.


Requested From: 
Date Requested: 6/21/2018

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