Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
IHC, IHC - Paraffin, Immunofluorescence, Western blot
Rabbit Polyclonal to Human O3FAR1 / GPR120
Western blot, ELISA
Human O3FAR1 / GPR120
Human (tested or 100% immunogen sequence identity)
Western blot (1:200)
Specificity and Use
O3FAR1 / GPR120 antibody was raised against human GPR120 amino acids 28-40 (FSDVKGDHRLVLA). Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon (100%), Monkey, Mouse, Rat, Panda, Ferret, Rabbit, Pig, Bovine (92%), Horse, Bat (85%).
Receptor for medium and long-chain free fatty acids (FFAs). Signals via a G(q)/G(11)-coupled pathway. Acts as a receptor for omega-3 fatty acids and mediates robust anti-inflammatory effects, particularly in macrophages and fat cells. The anti-inflammatory effects involve inhibition of TAK1 through a beta-arrestin 2 (ARRB2)/TAB1-dependent effect, but independent of the G(q)/G(11)-coupled pathway.