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NUP98

nucleoporin 98kDa

Signal-mediated nuclear import and export proceed through the nuclear pore complex (NPC), which is comprised of approximately 50 unique proteins collectively known as nucleoporins. The 98 kDa nucleoporin is generated through a biogenesis pathway that involves synthesis and proteolytic cleavage of a 186 kDa precursor protein. This cleavage results in the 98 kDa nucleoporin as well as a 96 kDa nucleoporin, both of which are localized to the nucleoplasmic side of the NPC. Rat studies show that the 98 kDa nucleoporin functions as one of several docking site nucleoporins of transport substrates. The human gene has been shown to fuse to several genes following chromosome translocations in acute myelogenous leukemia (AML) and T-cell acute lymphocytic leukemia (T-ALL). This gene is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Alternative splicing of this gene results in several transcript variants; however, not all variants have been fully described.

Gene Name: nucleoporin 98kDa
Synonyms: NUP98, ADAR2, ADIR2, Nucleoporin 98kD, Nup98-Nup96, Nucleoporin 98kDa, NUP196, NUP96
Target Sequences: NM_016320 NP_057404.2 P52948

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Antibodies (50)
ELISA Kits (7)
Proteins (4)
Primary (50)
Recombinant (4)
Sandwich (7)
NUP98 (61)
Human (43)
Mouse (27)
Rat (10)
Bat (3)
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Chicken (1)
Chimpanzee (6)
Dog (5)
Gibbon (3)
Guinea pig (1)
Horse (6)
Monkey (7)
Porcine (1)
Rabbit (7)
Zebrafish (3)
IHC (4)
IHC-P (4)
WB (39)
ELISA (10)
IF (2)
IP (7)
Peptide-ELISA (1)
rabbit (39)
mouse (11)
Product Group
IHCPlus (1)
IgG (17)
IgG1 (1)
IgG2a,k (7)
monoclonal mc (13)
polyclonal pc (37)
4G2 (1)
12 x 8-Well Microstrips (1)
96-Well Strip Plate (6)
APC (2)
APC Conjugated (3)
Biotin Conjugated (6)
Cy3 Conjugated (2)
Cy7 Conjugated (2)
FITC Conjugated (6)
HRP Conjugated (6)
PE Conjugated (3)
Unconjugated (22)
aa568-776 (8)
aa629-894 (8)
aa201-250 (4)
aa36-85 (4)
Leu518 (1)
Pro671 (1)
aa1-110 (1)
aa1650-1700 (1)
aa549-880 (1)
aa600-650 (1)
aa900-950 (1)
No (61)
Plasma (2)
Serum (2)
GST (1)
GST, N-terminus (1)
His-T7 (2)
Human (3)
Mouse (1)
E. coli (2)
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Purified (1)
NUP98 Antibody - Anti-NUP98 antibody IHC staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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NUP98 Rabbit anti-Human Polyclonal (aa201-250) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
NUP98 Antibody - Anti-NUP98 antibody IHC staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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NUP98 Rabbit anti-Human Polyclonal (aa201-250) (HRP) Antibody
Rabbit, Bovine, Rat, Horse, Gibbon, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
NUP98 Antibody - Anti-NUP98 antibody IHC staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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NUP98 Rabbit anti-Human Polyclonal (aa201-250) (Biotin) Antibody
Rabbit, Bovine, Rat, Horse, Gibbon, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
NUP98 Antibody - Anti-NUP98 antibody IHC staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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NUP98 Rabbit anti-Human Polyclonal (aa201-250) (FITC) Antibody
Rabbit, Bovine, Rat, Horse, Gibbon, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
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NUP98 Rabbit anti-Human Monoclonal (Pro671) Antibody
Mouse, Rat, Human
IF, IP, WB
Unconjugated
20 µl/$468; 100 µl/$702
NUP98 Protein - 12.5% SDS-PAGE of human NUP98 stained with Coomassie Blue
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Wheat Germ Extract
GST
92.4 kDa
10 µg/$479; 25 µg/$670
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NUP98 Rabbit anti-Human Monoclonal (Leu518) Antibody
Mouse, Rat, Human
IP, WB
Unconjugated
100 µl/$688
NUP98 Antibody - Western blot analysis of extracts of COLO 320 cells tissue, using NUP98 antibody.
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NUP98 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
20 µl/$275; 100 µl/$389; 200 µl/$503
NUP98 Antibody - Immunofluorescence staining of A549 cells at a dilution of 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4 °C.The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG (H+L) .
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NUP98 Rabbit anti-Human Polyclonal Antibody
Human
IF, WB
Unconjugated
50 µg/$294; 100 µg/$360
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NUP98 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IP, WB
Unconjugated
100 µg/$331
NUP98 Antibody - Western blot detection of NUP98 in Hela, Jurkat and MCF7 cell lysates using NUP98 mouse mAb (1:1000 diluted). Predicted band size: 98kDa. Observed band size: 98kDa.
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NUP98 Mouse anti-Human Monoclonal Antibody
Human
ELISA, WB
Unconjugated
50 µg/$332; 100 µg/$404; 200 µg/$505
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NUP98 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
NUP98 Antibody - Western blot detection of NUP98 in HeLa, Jurkat and MCF7 cell lysates using NUP98 mouse monoclonal antibody (1:1000 dilution). Predicted band size: 98kDa. Observed band size: 98kDa.
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NUP98 Mouse anti-Human Monoclonal Antibody
Human
IP, WB
Unconjugated
100 µl/$391
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NUP98 Rabbit anti-Human Polyclonal (aa900-950) Antibody
Human
IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
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NUP98 Rabbit anti-Human Polyclonal (aa600-650) Antibody
Human
IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
NUP98 Antibody - Western blot analysis NUP98 using MCF-7 whole cells lysates
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NUP98 Rabbit anti-Human Polyclonal Antibody
Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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NUP98 Mouse anti-Human Monoclonal (aa1-110) Antibody
Human
ELISA
Unconjugated
100 µg/$705
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NUP98 Mouse anti-Human Monoclonal (4G2) Antibody
Human
ELISA
Unconjugated
100 µg/$423
NUP98 Antibody - Western blot detection of NUP98 in Hela.
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NUP98 Mouse anti-Human Monoclonal Antibody
Mouse, Dog, Human
WB
Unconjugated
50 µl/$356; 100 µl/$461
NUP98 Antibody - Western blot of recombinant NUP98.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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NUP98 Rabbit anti-Mouse Polyclonal (aa568-776) Antibody
Mouse
WB
Unconjugated
100 µl/$306; 200 µl/$347; 500 µl/$484; 1 ml/$553; 2 ml/$737; 5 ml/$1,206
NUP98 Antibody - Western blot of recombinant NUP98.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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NUP98 Rabbit anti-Mouse Polyclonal (aa568-776) (APC) Antibody
Mouse
WB
APC Conjugated
100 µl/$402; 200 µl/$484; 500 µl/$834; 1 ml/$991; 2 ml/$1,277; 5 ml/$2,395
NUP98 Antibody - Western Blot (WB) analysis using Nup98 Monoclonal Antibody against HeLa, Jurkat, MCF7 cell lysate.
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NUP98 Mouse anti-Human Monoclonal Antibody
Mouse, Dog, Human
WB
Unconjugated
50 µg/$332; 100 µg/$404; 200 µg/$505
NUP98 Antibody - NUP98 antibody Western blot of Transfected 293T cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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NUP98 Rabbit anti-Human Polyclonal (aa36-85) Antibody
Human
WB
Unconjugated
100 µl/$424
NUP98 Antibody
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NUP98 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µl/$286; 100 µl/$321
NUP98 Antibody - NUP98 antibody Western blot. All lanes: Anti NUP98 at 0.5 ug/ml. Lane 1: Rat Liver Tissue Lysate at 50 ug. Lane 2: Mouse Liver Tissue Lysate at 50 ug. Lane 3: Mouse Lung Tissue Lysate at 50 ug. Lane 4: A549 Whole Cell Lysate at 40 ug. Lane 5: SMMC Whole Cell Lysate at 40 ug. Predicted band size: 98 kD. Observed band size: 98 kD.
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NUP98 Rabbit anti-Human Polyclonal (aa549-880) Antibody
Mouse, Rat, Human
WB
Unconjugated
10 µg/$318; 100 µg/$470
Viewing 1-25 of 61 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).