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Anti-NUMBLIKE / NUMBL Antibody (aa256-268) LS-C186566

Ordering

Wt. Vol. Conc. Price
100 µg - 0.5 mg/ml Unavailable

Most Popular NUMBLIKE / NUMBL Antibodies

Anti-NUMBLIKE / NUMBL Antibody (aa572-600) LS-C163065
Rabbit Polyclonal to Human NUMBLIKE / NUMBL
Human
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-NUMBLIKE / NUMBL Antibody (N-Terminus) IHC-plus™ LS-B8899
Rabbit Polyclonal (IgG) to Human NUMBLIKE / NUMBL
Human
IHC - Paraffin, ELISA
Unconjugated
Immunohistochemistry Image
Anti-NUMBLIKE / NUMBL Antibody (aa256-268) LS-C186566
Goat Polyclonal to Human NUMBLIKE / NUMBL
Human, Monkey, Mouse, Rat, Bovine, Dog, Guinea pig, Horse, Rabbit
IHC, ELISA
Unconjugated

100% Guaranteed 100% Guaranteed
Goat Polyclonal to Human NUMBLIKE / NUMBL
Human, Monkey, Mouse, Rat, Bovine, Dog, Guinea pig, Horse, Rabbit
IHC, ELISA
Unconjugated

Details

Human NUMBLIKE / NUMBL
Goat
Human, Monkey, Mouse, Rat, Bovine, Dog, Guinea pig, Horse, Rabbit (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • IHC
  • ELISA (1:16000)

Specificity and Use

NUMBLIKE / NUMBL antibody was raised against synthetic peptide C-PAQPGHVSPTPAT from an internal region of human NUMBLIKE / NUMBL (NP_004747.1). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Galago, Marmoset, Mouse, Rat, Ferret, Panda, Dog, Cat, Bovine, Horse, Rabbit, Guinea pig (100%); Opossum (85%).
LS-E27897 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C186566. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
aa256-268
Human NUMBLIKE / NUMBL
Peptide ELISA: antibody detection limit dilution 1:16000. Western blot: Approx 75kD band observed in Mouse fetal Brain lysates (calculated MW of 64.1kD according to Mouse NP_035080.2). The observed molecular weight corresponds to earlier findings in literature with different antibodies (Tao et al, Mol Biol Cell. 2012 Jul;23(14):2635-44. PMID: 22593207). Recommended concentration: 0.03-0.1 ug/ml. IHC: In paraffin embedded fetal Mouse Brain shows staining of lobes and fibres in the optic disc (first figure) and nervous fibres from the spinal metameric roots (second figure). Recommended concentration, 4-6 ug/ml.

Packaging

Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Store at -20°C. Minimize freezing and thawing.
For research use only.

About NUMBLIKE / NUMBL

Q9Y6R0 NM_004756 NP_004747.1

NUMBL Antibody, CTG3a Antibody, NBL Antibody, Numb homolog-like Antibody, Numb-like protein Antibody, Numb-related protein Antibody, NUMB-R Antibody, NUMBLIKE Antibody, TNRC23 Antibody, Numb (Drosophila) homolog-like Antibody, NUMBR Antibody, CAG3A Antibody, Numb homolog (Drosophila)-like Antibody

Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of embryonic neurogenesis. Also required postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity.

Requested From: 
Date Requested: 3/29/2017

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