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NTSR1 / NTR
neurotensin receptor 1 (high affinity)
NTR1, a Neurotensin Receptor, activates a phosphatidylinositol-calcium second messenger system in the central and peripheral nervous systems. It mediates the functions of neurotensin, such as hypotension, hyperglycemia, hypothermia, antinociception, and regulation of intestinal motility and secretion. Neurotensin Receptor 1 expression is enhanced in pancreatic cancer and in chronic pancreatitis (Wang et al, 2000). Two differentially glycosylated forms of the NT1 receptor have been identified in rats, a 54-kD form that is expressed from birth to adulthood, and a 52-kD form only detected at 10 and 15 days postnatal.
| Gene Name: | neurotensin receptor 1 (high affinity) |
| Family/Subfamily: | GPCR , Neurotensin |
| Synonyms: | NTSR1, Neurotensin receptor type 1, NT-1r, NT1 receptor, NTR, NTS1, Neurotensin receptor 1, NT-R-1, NTR1, NTRH, NTRR, Neurotensin receptor ntr1, NTS-1, Neurotensin type 1 receptor, NT receptor-1, RNTR1 |
| Target Sequences: | NM_002531 CAA49675.1 P30989 |
Publications (3)
1
IFN-ß alters neurotrophic factor expression in T cells isolated from multiple sclerosis patients - implication of novel neurotensin/NTSR1 pathway in neuroprotection. Soltys J, Knight J, Scharf E, Pitt D, Mao-Draayer Y. American journal of translational research. 2014 6:312-9. (IHC; Human)
[PubMed:24936223]
[PMC:PMC4058312]
Related Antibodies: LS-A938.
2
Co-localization patterns of neurotensin receptor 1 and tyrosine hydroxylase in brain regions involved in motivation and social behavior in male European starlings. Merullo DP, Spool JA, Zhao C, Riters LV. Journal of chemical neuroanatomy. 2018 April;89:1-10. [Full Text Article]
[PubMed:29407461]
[PMC:PMC5924578]
Related Antibodies: LS-B5255.
3
Characterisation of the Expression of Neurotensin and Its Receptors in Human Colorectal Cancer and Its Clinical Implications. Shengyang Qiu, Stella Nikolaou, Jie Zhu, Peter Jeffery, Robert Goldin, James Kinross, James L Alexander, Shahnawaz Rasheed, Paris Tekkis, Christos Kontovounisios. Biomolecules. 2020 August;10: [Full Text Article]
[PubMed:32764278]
[PMC:PMC7464404]
Related Antibodies: LS-A938.
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Neuroscience
NTSR1 / NTR Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Human
IHC, IHC-P
Unconjugated
50 µg/$440
NTSR1 / NTR Rabbit anti-Human Polyclonal (aa181-230) Antibody
Mouse, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
Neuroscience
Fast Shipping
NTSR1 / NTR Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$440
Fast Shipping
NTSR1 / NTR Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IHC, IHC-P
Unconjugated
50 µg/$460
NTSR1 / NTR Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA, IHC
Unconjugated
100 µg/$832
NTSR1 / NTR Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$321
NTSR1 / NTR Rabbit anti-Human Polyclonal (150-230 aa, Internal) Antibody
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
NTSR1 / NTR Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$832
NTSR1 / NTR Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
ELISA, WB
Unconjugated
100 µl/$801
NTSR1 / NTR Rabbit anti-Human Polyclonal (His218) Antibody
Mouse, Human
IF, IHC, WB
Unconjugated
50 µl/$321; 100 µl/$403
NTSR1 / NTR Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
NTSR1 / NTR Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF
Unconjugated
50 µg/$294; 100 µg/$360
NTSR1 / NTR Rabbit anti-Human Polyclonal (HRP) Antibody
Human
HRP Conjugated
50 µg/$294; 100 µg/$360
NTSR1 / NTR Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
Biotin Conjugated
50 µg/$294; 100 µg/$360
NTSR1 / NTR Rabbit anti-Human Polyclonal (FITC) Antibody
Human
FITC Conjugated
50 µg/$294; 100 µg/$360
NTSR1 / NTR Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA, WB
Unconjugated
100 µl/$801
NTSR1 / NTR Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
NTSR1 / NTR Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
100 µg/$357
NTSR1 / NTR Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µl/$356; 100 µl/$461
NTSR1 / NTR Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
NTSR1 / NTR Rabbit anti-Human Polyclonal (aa35-84) Antibody
Human
WB
Unconjugated
100 µl/$424
NTSR1 / NTR Rabbit anti-Human Polyclonal (aa35-84) (HRP) Antibody
Mouse, Guinea pig, Horse, Gibbon, Human, Chimpanzee
WB
HRP Conjugated
100 µl/$469
NTSR1 / NTR Rabbit anti-Human Polyclonal (aa35-84) (Biotin) Antibody
Mouse, Guinea pig, Horse, Gibbon, Human, Chimpanzee
WB
Biotin Conjugated
100 µl/$469
NTSR1 / NTR Rabbit anti-Human Polyclonal (aa35-84) (FITC) Antibody
Mouse, Guinea pig, Horse, Gibbon, Human, Chimpanzee
WB
FITC Conjugated
100 µl/$469
NTSR1 / NTR Goat anti-Human Polyclonal Antibody
Human
IE
Unconjugated
2 ml/$277
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