LSBio The Immunohistochemistry Antibody Company
Products
  • Antibodies
  • All Antibodies
  • Primary Antibodies
  • Secondary Antibodies
  • IHC-plus Antibodies
  • Isotype Control Antibodies
  • ELISA Kits
  • All Kits
  • Sandwich ELISA Kits
  • Competitive EIA Kits
  • Cell-Based ELISA Kits
  • DNA-Binding ELISA Kits
  • Direct ELISA Kits
  • Functional ELISA Kits
  • Phospho-Specific ELISA Kits
  • Custom ELISA Kits
  • Proteins
  • All Proteins
  • Recombinant Proteins
  • Native Proteins
  • Over-expression Lysates
  • Cell and Tissue Lysates
  • Bio-active Proteins
  • Animal-free Proteins
  • Synthetic Peptides
  • Immunohistochemistry
  • Comprehensive IHC Reports
  • Custom IHC Services
  • TCR Screening Services
  • IHC-plus Antibodies
  • Other
  • Blocking Peptides
Services
  • Immunohistochemistry Services

  • Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

  • TCR Screening Services

  • Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Have a question? CustomerSupport@LSBio.com
Resources
  • Purchasing
  • Product Ordering Terms and Conditions
  • Holiday Schedule
  • About the LSBio Guarantee
  • About Our Rewards Program
  • Reference Material
  • About LSBio (LifeSpan BioSciences Inc.)
  • About Our 2-million Specimen Tissue Bank
  • About Our IHC Validation Process
  • About Our IHC-plus™ Immunohistochemistry Protocol
  • Publications
  • Secure Logins
  • Login to Our Secure FTP Site
  • Login to Our IHC Database
Distributors
Contact Us

LSBio
2401 Fourth Avenue Suite 900
Seattle WA 98121

Phone: 866-819-4732 (Toll Free North America)
206-374-1102 (International)

Fax: 866-206-6909 (Toll Free North America)
206-577-4565 (International)
How to Buy - Details about how to buy our products.

Orders@LSBio.com - To submit a new order.

Customer.Support@LSBio.com - To submit questions about existing orders, pricing, availability, bulk quotes, proforma invoice requests, or other billing issues.

Technical.Support@LSBio.com - To request technical information requests about an LSBio product or its application.

Sales@LSBio.com - To request information about fee-for-service contract IHC studies, IHC reports, distribution agreements, or general business development.

Worldwide Distributors List - To find your local distributor if you're not within the United States.
Quick Order ▾
View Cart

Anti-NTRK3 / TRKC Antibody (C-Terminus) LS-C60105

Ordering

Wt. Vol. Conc. Price
100 µg - 1.53 mg/ml $405
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular NTRK3 / TRKC Antibodies

Anti-NTRK3 / TRKC Antibody (PE) LS-C39860
Goat Polyclonal (IgG) to Human NTRK3 / TRKC
Human
Flow Cytometry
PE Conjugated
Anti-NTRK3 / TRKC Antibody (aa1-429) IHC-plus™ LS-B2176
Goat Polyclonal (IgG) to Rat NTRK3 / TRKC
Rat, Human, Mouse
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-NTRK3 / TRKC Antibody (C-Terminus) IHC-plus™ LS-B13160
Rabbit Polyclonal (IgG) to Human NTRK3 / TRKC
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Horse, Pig, Chicken, Xenopus
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry - Paraffin Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Mouse NTRK3 / TRKC
Mouse, Human, Rat
Western blot, ELISA
Unconjugated

Details

Mouse NTRK3 / TRKC
Rabbit
Mouse, Human, Rat (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • Western blot (1:1000 - 1:10000)
  • ELISA (1:5000 - 1:20000)

Specificity and Use

NTRK3 / TRKC antibody was raised against synthetic peptide corresponding to amino acids near the carboxyl terminus of mouse TrkCT1 protein.
C-Terminus
mouse TrkCT1 protein. A BLAST analysis was used to suggest cross-reactivity with TrkCT1 protein from human, mouse and rat based on 100% homology with the immunizing sequence. Reactivity against homologs from other sources is not known
This affinity purified antibody has been tested for use in ELISA and western blotting. Specific conditions for reactivity should be optimized by the end user. While the predicted molecular weight for TrkCT1 is approximately 70 kD, the protein has been reported to migrate at about 95 kD on western blots. The molecular weight noted for TrkCT1 depends somewhat upon the cell lysate or extract used for western blotting, and this variation may be due to post-translational modifications of the protein.

Packaging

0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2, 0.01% sodium azide.
Long term: -20°C; Short term: -20°C
For research use only.

About NTRK3 / TRKC

Q16288 NM_002530 NP_002521.2

NTRK3 Antibody, ETV6-NTRK3 fusion Antibody, gp145-TrkC Antibody, Neurotrophin 3 receptor Antibody, TRKC Antibody, TrkC tyrosine kinase Antibody, NT-3 growth factor receptor Antibody, NT3 growth factor receptor Antibody, Tyrosine kinase receptor C Antibody, Pan Trk Antibody, gp145(trkC) Antibody, Trk-C Antibody

NTRK3 / TRKC is a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers.

Western blot

Western blot
Anti-TrkCT1 Antibody - Western Blot. Western blot of affinity purified anti-TrkCT1 to detect endogenous TrkCT1 in mouse cortex lysate (Lane 1). Lane 2 is TrkCT1 knock-out cortex lysate. Cell extracts were resolved by electrophoresis and transferred to nitrocellulose. The membrane was probed with the primary antibody at a 1:6000 dilution. Personal Communication, V. Coppola, CCRNCI, Frederick, MD.

Western blot

Western blot
Anti-TrkCT1 Antibody - Immunoprecipitation/Western Blot. Mouse cortex lysate was immunoprecipitated with anti-TrkCT1 antibody and further blotted with affinity purified anti-TrkCT1. Lane 1 is wild-type cortex lysate, Lane 2 is Tamalin knock-out cortex lysate, and Lane 3 is TrkCT1 knock-out cortex lysate. The membrane was probed with the primary antibody at a 1:6000 dilution. Personal Communication, V. Coppola, CCR-NCI, Frederick, MD.

Western blot

Western blot
Anti-TrkCT1 Antibody - Western Blot. Western blot of affinity purified anti-TrkCT1 to detect over-expressed TrkCT1 in HEK293 cells (Lane 2, arrowhead). Lane 1 is a non-transfected control. Cell extracts were resolved by electrophoresis and transferred to nitrocellulose. The membrane was probed with the primary antibody at a 1:3000 dilution. Personal Communication, V. Coppola, CCR-NCI, Frederick, MD.
 

Requested From: United States
Date Requested: 12/3/2016

Get Social With Us! Follow us on Facebook Follow us on Google+ Follow us on LinkedIn
Copyright © 2016 LifeSpan BioSciences, Inc. All Rights Reserved Privacy Policy
Catalog Number